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  1. No Access

    Article

    Nocturnal frontal lobe epilepsy presenting with restless leg syndrome-like symptoms

    We describe the case of a 22-year-old male affected by NFLE reporting paroxysmal RLS-like symptoms. The patient was referred to our Sleep Center due to nocturnal paresthesias and cramps involving the left leg ...

    Irene Aricò, Rosaria Condurso, Francesca Granata, Lino Nobili in Neurological Sciences (2011)

  2. Article

    Open Access

    Studying functional networks in human brain through intracerebral spontaneous EEG

    Gabriele Arnulfo, Andrea Pigorini, Marcello Massimini, Lino Nobili in BMC Neuroscience (2011)

  3. No Access

    Chapter and Conference Paper

    Integrating Neural Networks and Chaotic Measurements for Modelling Epileptic Brain

    In the last 20 years a lot of works in literature analysed and proposed several methods capable to predict the occurrence of seizures from the electroencephalogram (EEG) of epileptic patients. One of the best ...

    Maurizio Fiasché, Stefan Schliebs in Artificial Neural Networks and Machine Lea… (2012)

  4. Article

    Electroclinical, MRI and surgical outcomes in 100 epileptic patients with type II FCD

    Focal cortical dysplasias (FCDs) are highly epileptogenic malformations associated with drug-resistant epilepsy, susceptible to surgical treatment. Among the different types of FCD, the type II includes two su...

    Laura Tassi, Rita Garbelli, Nadia Colombo, Manuela Bramerio in Epileptic Disorders (2012)

  5. No Access

    Article

    Missense mutations in the sodium-gated potassium channel gene KCNT1 cause severe autosomal dominant nocturnal frontal lobe epilepsy

    Samuel Berkovic and colleagues report the identification of missense mutations in KCNT1, which encodes a sodium-gated potassium channel, that cause severe autosomal dominant nocturnal frontal lobe epilepsy.

    Sarah E Heron, Katherine R Smith, Melanie Bahlo, Lino Nobili in Nature Genetics (2012)

  6. No Access

    Chapter and Conference Paper

    A Comparison between the Use of ESNN on Long Stereo-EEG Recordings and Their Largest Lyapunov Exponent Profiles for Epileptic Brain Analysis

    In the last 25 years many works in literature about the capability to detect or predict the occurrence of epileptic seizures, starting from the electroencephalogram (EEG) signal analysis, have often hypothesiz...

    Maurizio Fiasché, Lino Nobili, Bruno Apolloni in Neural Information Processing (2013)

  7. Article

    Open Access

    Characterizing brain states with Granger causality

    Adam B Barrett, Lionel Barnett, Paul Chorley, Andrea Pigorini in BMC Neuroscience (2013)

  8. Article

    Ictal EEG modifications in temporal lobe epilepsy

    Temporal lobe epilepsy is the most common type of epilepsy in adults with medically intractable, localisation-related epilepsy, amenable to surgery. Together with clinical and neuroimaging data, presurgical ic...

    Veronica Pelliccia, Roberto Mai, Stefano Francione, Francesca Gozzo in Epileptic Disorders (2013)

  9. No Access

    Book

  10. No Access

    Chapter

    Lifestyle and Habits

    Nowadays there seems to be a growing attention to encouraging healthy lifestyles. Sleep is a key indicator of health-related habits. Sleep disturbances are considered important risk factors for several medical...

    Sergio Garbarino, Lino Nobili in Sleepiness and Human Impact Assessment (2014)

  11. No Access

    Chapter

    Errors and Accidents

    Sleep deprivation affects performance outcomes across a wide range of cognitive domains. Sleepiness and fatigue, caused by sleep loss, extended work and wakefulness, circadian misalignment, and sleep disorders...

    Pierre Philip, Cyril Chaufton, Lino Nobili in Sleepiness and Human Impact Assessment (2014)

  12. No Access

    Chapter

    Parasomnias

    Parasomnias are frequent sleep disorders characterized by abnormal behaviors, physical events, or experiences occurring during different sleep stages. The International classification of sleep disorders subdiv...

    Giuseppe Plazzi, Lino Nobili in Sleepiness and Human Impact Assessment (2014)

  13. Article

    Nocturnal Frontal Lobe Epilepsy

    Nocturnal frontal lobe epilepsy (NFLE) is a syndrome of heterogeneous etiology, characterized by the occurrence of sleep-related seizures with different complexity and duration. Genetic, lesional, and cryptoge...

    Lino Nobili, Paola Proserpio, Romina Combi in Current Neurology and Neuroscience Reports (2014)

  14. No Access

    Chapter

    Sleep and Epilepsy

    This chapter outlines an interaction between sleep and epilepsy including effect of sleep on epilepsy, epilepsy on sleep, and antiepileptic medication on sleep, preceded by a brief discussion about mechanism o...

    Sudhansu Chokroverty, Lino Nobili in Sleep Disorders Medicine (2017)

  15. Article

    Open Access

    Integrated Imaginative Distention Therapy to Cope with Fatigue. DIMMI SI Study: The First Randomized Controlled Trial in Multiple Sclerosis

    Fatigue is a frequent, disabling, and difficult to treat symptom in neurological disease and in other stress-related conditions; Integrated Imaginative Distention (IID) is a therapy combining muscular and imag...

    Annalisa Sgoifo, Angelo Bignamini, Loredana La Mantia in Neurology and Therapy (2017)

  16. No Access

    Article

    NREM sleep parasomnias as disorders of sleep-state dissociation

    Non-rapid eye movement (NREM) sleep parasomnias (or NREM parasomnias) are fascinating disorders with mysterious neurobiological substrates. These conditions are common and often severe, with social, personal a...

    Anna Castelnovo, Régis Lopez, Paola Proserpio, Lino Nobili in Nature Reviews Neurology (2018)

  17. No Access

    Chapter

    Local Cortical Activations During REM Sleep and Implications for RBD

    Different neuroimaging and intracerebral EEG studies have shown that brain activity during physiologic REM sleep in humans is not temporally and spatially homogeneous. Indeed, some brain regions (i.e., motor c...

    Paola Proserpio, Michele Terzaghi in Rapid-Eye-Movement Sleep Behavior Disorder (2019)

  18. No Access

    Article

    Short sleep duration and cardiometabolic risk: from pathophysiology to clinical evidence

    Short sleep duration has a substantial influence on the overall health of an individual. Short sleep time can be a consequence of lifestyle habits, environmental factors, or the presence of a sleep disorder, s...

    Eleonora Tobaldini, Elisa M. Fiorelli, Monica Solbiati in Nature Reviews Cardiology (2019)

  19. No Access

    Article

    Dissecting the neurological phenotype in children with callosal agenesis, interhemispheric cysts and malformations of cortical development

    To describe the neurological phenotype of children with prenatal diagnosis of agenesis of corpus callosum (ACC) and interhemispheric cysts associated with malformations of cortical development (MCD).

    Sara Uccella, Andrea Accogli, Domenico Tortora in Journal of Neurology (2019)

  20. No Access

    Article

    Prognostic factors of postoperative seizure outcome in patients with temporal lobe epilepsy and normal magnetic resonance imaging

    To retrospectively analyse a single-centre consecutive surgical series of patients with temporal lobe epilepsy (TLE) and negative MRI. To identify factors associated with postoperative seizure outcome among se...

    Valeria Mariani, Martina Revay, Piergiorgio D’Orio, Michele Rizzi in Journal of Neurology (2019)

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