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  1. Article

    Effects of the Lower Airway Secretions on Airway Opening Pressures and Suction Pressures in Critically Ill COVID-19 Patients: A Computational Simulation

    In patients with critically ill COVID-19 pneumonia, lower airways are filled with plenty of highly viscous exudates or mucus, leading to airway occlusion. The estimation of airway opening pressures and effecti...

    Zhenglong Chen, Ming Zhong, Li Jiang, Nanshan Chen in Annals of Biomedical Engineering (2020)

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    Article

    Reproducibility and Radiation Effect of High-Resolution In Vivo Micro Computed Tomography Imaging of the Mouse Lumbar Vertebra and Long Bone

    A moderate radiation dose, in vivo µCT scanning protocol was developed and validated for long-term monitoring of multiple skeletal sites (femur, tibia, vertebra) in mice. A customized, 3D printed mouse holder was...

    Hongbo Zhao, Chih-Chiang Chang, Yang Liu, Youwen Yang in Annals of Biomedical Engineering (2020)

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    Distinctive pharmacological differences between liver cancer cell lines HepG2 and Hep3B

    As cellular models for in vitro liver cancer and toxicity studies, HepG2 and Hep3B are the two most frequently used liver cancer cell lines. Because of their similarities they are often treated as the same in ...

    Guo-Hua Qiu, **ao** **e, Fang Xu, **aohao Shi, Yue Wang, Linhong Deng in Cytotechnology (2015)

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    Article

    Upregulation of SDF-1 is Associated with Atherosclerosis Lesions Induced by LDL Concentration Polarization

    Previous numerical simulations on low-density lipoprotein (LDL) concentration polarization in the arterial system indicated that LDL concentration polarization might play an important role in the genesis and d...

    Dangheng Wei, Guixue Wang, Chaojun Tang, Juhui Qiu in Annals of Biomedical Engineering (2012)