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Article
Open AccessElevated serum B-cell activator factor levels predict rapid progressive interstitial lung disease in anti-melanoma differentiation associated protein 5 antibody positive dermatomyositis
Rapid progressive interstitial lung disease (RP-ILD) is the leading cause of anti-melanoma differentiation associated protein 5 antibody positive dermatomyositis (anti-MDA5+DM) related death. Elevated serum B-cel...
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Article
Open AccessProteomic profiling identifies SPP1 associated with rapidly progressive interstitial lung disease in anti-MDA5-positive dermatomyositis
Anti-melanoma differentiation-associated gene five antibody positive (MDA5+) dermatomyositis (DM) is significantly associated with rapidly progressive interstitial lung disease (RP-ILD). Early detection of RP-ILD...
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Article
Gender differences in patients with anti-MDA5-positive dermatomyositis: a cohort study of 251 cases
To investigate the impact of sex differences on the clinical characteristics and prognosis of patients with anti-melanoma differentiation-associated gene 5-positive dermatomyositis (MDA5+ DM).
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Chapter and Conference Paper
A Reinforcement Learning Based Approach to Identify Resource Bottlenecks for Multiple Services Interactions in Cloud Computing Environments
Cloud service providers are provisioning resources including a variety of virtual machine instances to support customers that migrate their services to the cloud. From the customers’ perspective, selecting the...
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Article
Silver binding in argentiferous manganese oxide minerals investigated by synchrotron radiation X-ray absorption spectroscopy
The knowledge of the nature of silver occurrence and sites in argentiferous manganese oxides is significant for develo** better process to extract silver from manganese-silver ores. Synchrotron radiation has...
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Article
Open AccessCorrection to: Adiponectin aggravates bone erosion by promoting osteopontin production in synovial tissue of rheumatoid arthritis
Unfortunately, after publication of this article [1], it was noticed that the panel for Fig. 4b was inadvertently obscured during the production process. The full, correct Fig. 4 can be seen below and the orig...
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Article
LC-MS-based serum metabolomics reveals a distinctive signature in patients with rheumatoid arthritis
Metabolomics has been applied to explore altered metabolite profiles in disease and identify unique metabolic signatures in recent years. We aim to characterize the metabolic profile of rheumatoid arthritis pa...
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Article
Open AccessAdiponectin aggravates bone erosion by promoting osteopontin production in synovial tissue of rheumatoid arthritis
We have previously reported that adiponectin (AD), an adipokine that is secreted by adipocytes, correlates well with progressive bone erosion in rheumatoid arthritis (RA). The exact mechanism of AD in promotin...
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Article
Open AccessModulation of IL-6 induced RANKL expression in arthritic synovium by a transcription factor SOX5
Receptor activator of nuclear factor κB ligand (RANKL) is critically involved in bone erosion of rheumatoid arthritis (RA). We previously reported association between younger age at onset of RA and a RANKL promot...
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Article
The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters
Recent studies have boosted our understanding of long noncoding RNAs (lncRNAs) in numerous biological processes, but few have examined their roles in somatic cell reprogramming. Through expression profiling an...
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Article
Open AccessIL-29 enhances Toll-like receptor-mediated IL-6 and IL-8 production by the synovial fibroblasts from rheumatoid arthritis patients
We previously reported that IL-29, a newly described member of interferon (IFN) family, was overexpressed in blood and synovium of rheumatoid arthritis (RA) patients and triggered proinflammatory cytokine IL-6...
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Article
Open AccessInterleukin-29 modulates proinflammatory cytokine production in synovial inflammation of rheumatoid arthritis
The immunoregulatory function of interleukin (IL)-29 has recently been recognized. However, little is known about the involvement of IL-29 in the pathogenesis of rheumatoid arthritis (RA). This study aimed to ...
