-
Article
Open AccessHierarchical Reinforcement Learning from Demonstration via Reachability-Based Reward Sha**
Hierarchical reinforcement learning (HRL) has achieved remarkable success and significant progress in complex and long-term decision-making problems. However, HRL training typically entails substantial computa...
-
Article
Open AccessSPADE: spatial deconvolution for domain specific cell-type estimation
Understanding gene expression in different cell types within their spatial context is a key goal in genomics research. SPADE (SPAtial DEconvolution), our proposed method, addresses this by integrating spatial ...
-
Article
PAC-Bayesian offline Meta-reinforcement learning
Meta-reinforcement learning (Meta-RL) utilizes shared structure among tasks to enable rapid adaptation to new tasks with only a little experience. However, most existing Meta-RL algorithms lack theoretical gen...
-
Article
Open AccessEnsemble dimensionality reduction and feature gene extraction for single-cell RNA-seq data
Single-cell RNA sequencing (scRNA-seq) technologies allow researchers to uncover the biological states of a single cell at high resolution. For computational efficiency and easy visualization, dimensionality r...
-
Chapter and Conference Paper
Race Classification Based Iris Image Segmentation
Iris segmentation is an essential precondition for biometric authentication systems based on iris recognition and dramatically affects the accuracy of personal identification. Due to various noises during iris...
-
Chapter
Performance Evaluation of Normalization Approaches for Metagenomic Compositional Data on Differential Abundance Analysis
Background: In recent years, metagenomics, as a combination of research techniques without the process of cultivation, has become more and more popular in studying the genomic/genetic variation of microbes in en...
-
Article
Development and Validation of a Sensitive Indirect Competitive Enzyme-Linked Immunosorbent Assay for the Screening of Florfenicol and Thiamphenicol in Edible Animal Tissue and Feed
To monitor the illegal use of florfenicol (FF) and thiamphenicol (TAP) in edible animal tissue and feed, a sensitive monoclonal antibody-based indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) ...
-
Article
Open AccessAccurate genome relative abundance estimation for closely related species in a metagenomic sample
Metagenomics has a great potential to discover previously unattainable information about microbial communities. An important prerequisite for such discoveries is to accurately estimate the composition of micro...
-
Article
Open AccessDetection of rare functional variants using group ISIS
Genome-wide association studies have been firmly established in investigations of the associations between common genetic variants and complex traits or diseases. However, a large portion of complex traits and...
-
Article
Gene expression analysis at the intersection of ploidy and hybridity in maize
Heterosis and polyploidy are two important aspects of plant evolution. To examine these issues, we conducted a global gene expression study of a maize ploidy series as well as a set of tetraploid inbred and hy...
-
Article
Cationic conjugated polymers for homogeneous and sensitive fluorescence detection of hyaluronidase
The cationic charged water-soluble polyfluorenes containing 2,1,3-benzothiadiazole (BT) units (P1–3) have been synthesized and characterized. These polymers demonstrate intramolecular energy transfer from the ...
-
Chapter and Conference Paper
Reversible Watermarking Based on Statistical Quantity Histogram
The histogram shifting based reversible watermarking techniques have attracted increasing interests due to their low computational complexity, high visual quality and considerable capacity. However, those meth...
-
Article
Analysis of gene expression profiles in response to Sclerotinia sclerotiorum in Brassica napus
Sclerotinia sclerotiorum is a necrotrophic plant pathogen which causes serious disease in agronomically important crop species. The molecular basis of plant defense to this pathogen is po...
