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  1. Article

    Open Access

    Fibronectin and laminin promote differentiation of human mesenchymal stem cells into insulin producing cells through activating Akt and ERK

    Islet transplantation provides a promising cure for Type 1 diabetes; however it is limited by a shortage of pancreas donors. Bone marrow-derived multipotent mesenchymal stem cells (MSCs) offer renewable cells ...

    Hsiao-Yun Lin, Chih-Chien Tsai, Ling-Lan Chen in Journal of Biomedical Science (2010)

  2. No Access

    Article

    Apoptosis in chondrogenesis of human mesenchymal stem cells: effect of serum and medium supplements

    Apoptosis is an inevitable process during development and is evident in the formation of articular cartilage and endochondral ossification of growth plate. Mesenchymal stem cells (MSCs) can serve as alternativ...

    Chien-Yuan Wang, Ling-Lan Chen, Pei-Yin Kuo, Jia-Ling Chang, Yng-Jiin Wang in Apoptosis (2010)

  3. No Access

    Article

    Genistein inhibits the inward rectifying potassium current in guinea pig ventricular myocytes

    Genistein is an isoflavone with potent inhibitory activity on protein tyrosine kinase. Previous studies have shown that genistein has additional effects, among which the direct blocking effects on various ioni...

    Chern-En Chiang Md, PhD, Hsiang-Ning Luk, Ling-Lan Chen in Journal of Biomedical Science (2002)