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    Article

    Subgroup characteristics of insular low-grade glioma based on clinical and molecular analysis of 42 cases

    Although the classification of insular glioma has been established based on the anatomical location in order to facilitate personalized surgical resection, the diagnosis based on anatomical and functional char...

    Chao Tang, Zhen-yu Zhang, Ling-chao Chen, Zelin Sun, Yi Zhang in Journal of Neuro-Oncology (2016)

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    Article

    TRIM28 as an independent prognostic marker plays critical roles in glioma progression

    Tripartite motif (TRIM) proteins are involved in tumorigenesis. Here, we examined the expression, biological function, and clinical significance of tripartite motif containing 28 (TRIM28) in glioma, a locally ...

    Zeng-**n Qi, Jia-Jun Cai, Ling-Chao Chen, Qi Yue, Yan Gong in Journal of Neuro-Oncology (2016)

  3. Article

    Open Access

    MicroRNA-566 activates EGFR signaling and its inhibition sensitizes glioblastoma cells to nimotuzumab

    Epidermal growth factor receptor (EGFR) is amplified in 40% of human glioblastomas. However, most glioblastoma patients respond poorly to anti-EGFR therapy. MicroRNAs can function as either oncogenes or tumor ...

    Kai-Liang Zhang, Xuan Zhou, Lei Han, Lu-Yue Chen, Ling-Chao Chen in Molecular Cancer (2014)