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Article

Senescence-associated secretory factors induced by cisplatin in melanoma cells promote non-senescent melanoma cell growth through activation of the ERK1/2-RSK1 pathway

Although targeted therapy and immunotherapy greatly improve the outcome of melanoma, drug resistance and low response rates still maintain the unsubstitutability of traditional chemotherapy. Cisplatin (CDDP) i...

Xuerong Sun, Benyan Shi, Huiling Zheng, Ling Min, Jie Yang… in Cell Death & Disease (2018)