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Article
Exposure to the Saturated Free Fatty Acid Palmitate Alters BV-2 Microglia Inflammatory Response
Elevated levels of free fatty acids (FFAs) in plasma and increased incidence of chronic systemic inflammation are associated with obesity. In the brain, activated microglia are believed to play different roles...
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Article
Open AccessGLP-1 secretion by microglial cells and decreased CNS expression in obesity
Type 2 diabetes (T2D) is a strong risk factor for develo** neurodegenerative pathologies. T2D patients have a deficiency in the intestinal incretin hormone GLP-1, which has been shown to exert neuroprotectiv...
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Article
Open AccessThe CCAAT/enhancer binding protein (C/EBP) δ is differently regulated by fibrillar and oligomeric forms of the Alzheimer amyloid-β peptide
The transcription factors CCAAT/enhancer binding proteins (C/EBP) α, β and δ have been shown to be expressed in brain and to be involved in regulation of inflammatory genes in concert with nuclear factor κB (N...
