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  1. Article

    Open Access

    STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia

    STAT3 and HIF1α are two fundamental transcription factors involved in many merging processes, like angiogenesis, metabolism, and cell differentiation. Notably, under pathological conditions, the two factors ha...

    Alberto Dinarello, Riccardo Massimiliano Betto, Linda Diamante in Cell Death Discovery (2023)

  2. Article

    Open Access

    BrewerIX enables allelic expression analysis of imprinted and X-linked genes from bulk and single-cell transcriptomes

    Genomic imprinting and X chromosome inactivation (XCI) are two prototypical epigenetic mechanisms whereby a set of genes is expressed mono-allelically in order to fine-tune their expression levels. Defects in ...

    Paolo Martini, Gabriele Sales, Linda Diamante, Valentina Perrera in Communications Biology (2022)