76 Result(s)
within
Lin**g Cheng
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessEffect of manual OCTA segmentation correction to improve image quality and visibility of choroidal neovascularization in AMD
In this retrospective case series on neovascular age-related macular degeneration (nAMD), we aimed to improve Choroidal Neovascularization (CNV) visualization in Optical Coherence Tomography Angiography (OCTA)...
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Open AccessA static precise single-point positioning method based on carrier phase zero-baseline self-differencing
Satellite navigation positioning has become an indispensable component of everyday life, where precise pinpointing and rapid convergence are crucial in delivering timely and accurate location information. Howe...
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Article
Open AccessFiring feature-driven neural circuits with scalable memristive neurons for robotic obstacle avoidance
Neural circuits with specific structures and diverse neuronal firing features are the foundation for supporting intelligent tasks in biology and are regarded as the driver for catalyzing next-generation artifi...
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Open AccessA psychometric assessment of a novel scale for evaluating vaccination attitudes amidst a major public health crisis
Despite abundant scientific evidence supporting immunization benefits, vaccine hesitancy remains a significant global health concern, particularly during public health crises. Exploring public attitudes toward...
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Open AccessDisparate macrophage responses are linked to infection outcome of Hantan virus in humans or rodents
Hantaan virus (HTNV) is asymptomatically carried by rodents, yet causes lethal hemorrhagic fever with renal syndrome in humans, the underlying mechanisms of which remain to be elucidated. Here, we show that di...
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Article
Ligand recognition and G-protein coupling of trace amine receptor TAAR1
Trace-amine-associated receptors (TAARs), a group of biogenic amine receptors, have essential roles in neurological and metabolic homeostasis1. They recognize diverse endogenous trace amines and subsequently acti...
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Open AccessMindfulness and job performance in Chinese nonprofit workers: mediation effects of PANA and work engagement
Despite the rapid growth of the Chinese nonprofit sector within the last 20 years, research shows Chinese nonprofit employees experience high rates of burnout and turnover. This has led to an increase in organ...
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Open AccessRetraction Note: SARI inhibits angiogenesis and tumour growth of human colon cancer through directly targeting ceruloplasmin
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Open AccessRetinal tissue and microvasculature loss in COVID-19 infection
This cross-sectional study aimed to investigate the hypothesis that permanent capillary damage may underlie the long-term COVID-19 sequela by quantifying the retinal vessel integrity. Participants were divided...
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Open AccessProspect of acromegaly therapy: molecular mechanism of clinical drugs octreotide and paltusotine
Somatostatin receptor 2 (SSTR2) is highly expressed in neuroendocrine tumors and represents as a therapeutic target. Several peptide analogs mimicking the endogenous ligand somatostatin are available for clini...
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Article
Open AccessBroadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses
As SARS-CoV-2 Omicron and other variants of concern (VOCs) continue spreading worldwide, development of antibodies and vaccines to confer broad and protective activity is a global priority. Here, we report on ...
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Open AccessAmplification of integrated microscopic motions of high-density [2]rotaxanes in mechanically interlocked networks
Integrating individual microscopic motion to perform tasks in macroscopic sale is common in living organisms. However, develo** artificial materials in which molecular-level motions could be amplified to beh...
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Open AccessIdentifying driving factors of urban land expansion using Google Earth Engine and machine-learning approaches in Mentougou District, China
The research on driving mechanisms of urban land expansion is hot topic of land science. However, the relative importance of anthropogenic-natural factors and how they affect urban land expansion change are st...
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Open AccessAddendum: Genome evolution and diversity of wild and cultivated potatoes
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Open AccessNovel mechanisms underlying inhibition of inflammation-induced angiogenesis by dexamethasone and gentamicin via PI3K/AKT/NF-κB/VEGF pathways in acute radiation proctitis
Acute radiation proctitis (ARP) is one of the most common complications of pelvic radiotherapy attributed to radiation exposure. The mechanisms of ARP are related to inflammation, angiogenesis, and so on. In t...
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Open AccessGraph pangenome captures missing heritability and empowers tomato breeding
Missing heritability in genome-wide association studies defines a major problem in genetic analyses of complex biological traits1,2. The solution to this problem is to identify all causal genetic variants and to ...
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Open AccessGenome evolution and diversity of wild and cultivated potatoes
Potato (Solanum tuberosum L.) is the world’s most important non-cereal food crop, and the vast majority of commercially grown cultivars are highly heterozygous tetraploids. Advances in diploid hybrid breeding bas...
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Chemical reprogramming of human somatic cells to pluripotent stem cells
Cellular reprogramming can manipulate the identity of cells to generate the desired cell types1–3. The use of cell intrinsic components, including oocyte cytoplasm and transcription factors, can enforce somatic c...
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Article
Open AccessChanges of plasma nitric oxide, endothelin-1, and blood coagulation following intravitreal conbercept
Intravitreal anti-VEGF (anti-vascular endothelial growth factor) biologics have revolutionized the pharmacological management of chorioretinal diseases. However, the systemic adverse events such as stroke or b...
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Article
Open AccessIntegrated metabolic and microbial analysis reveals host–microbial interactions in IgE-mediated childhood asthma
A metabolomics-based approach to address the molecular mechanism of childhood asthma with immunoglobulin E (IgE) or allergen sensitization related to microbiome in the airways remains lacking. Fifty-three chil...
