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840 Result(s)
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Article
Prevention of HIV-2 and SIVsm infection by passive immunization in cynomolgus monkeys
INFECTION of macaques with simian immunodeficiency virus (SIV)1,2 and human immunodeficiency virus type 2 (HIV-2) 3,4 are useful models for studies of immunotherapy and vaccination against HIV as well as for test...
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Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages
Analysis of mice carrying mutant T-cell antigen receptor (TCP) genes indicates that TCP-β gene rearrangement or expression is critical for the differentiation of CD4− CD8− thymocytes to CD4+CD8+ thymocytes, as we...
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The synthesis of dialdehydes from dicarboxylic acids via imidazolines
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Male eye span in stalk-eyed flies indicates genetic quality by meiotic drive suppression
In some species, females choose mates possessing ornaments that predict offspring survival1,2,3,4,5. However, sexual selection by female preference for male genetic quality6,7,8 remains controversial because conv...
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Optical properties of NdxGd1−xAl3(BO3)4 crystal
The optical properties of NdxGd1-xAl3(BO3)4(NGAB) crystal are reported. The refractive index of it were mesured by V-prism method. The absorption spectra and the flourescence specra of NGAB were also obtained. Th...
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Thermodynamic study on elimination of platinum inclusions in phosphate laser glasses for inertial confinement fusion applications
A new method to calculate the formation enthalpies and free energies of compounds based on standard electromotive force of cation, φ0, and free energies of formation, †G 298 0 ...
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Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing
Nicastrin, a transmembrane glycoprotein, forms high molecular weight complexes with presenilin 1 and presenilin 2. Suppression of nicastrin expression in Caenorhabditis elegans embryos induces a subset of notch/...
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The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors
Migration is a basic feature of many cell types in a wide range of species1. Since the 1800s, cell migration has been proposed to occur in the nervous and immune systems2,3, and distinct molecular cues for mammal...
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Article
Cloning and functional research of renal cell carcinoma related novel gene—GYLZ-RCC18
After the renal cell carcinoma related novel gene fragmentGYLZ-RCC18 was cloned by using suppression subtractive hybridization (SSH), we used the SMART RACE technology to clone the full length ofGYLZ-RCC18 and pe...
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Article
Evolutionary conservation ofDmrt gene family in amphibians, reptiles and birds
Sex determining geneMab-3 ofC. elegans anddoublesex ofDrosophila contain a common DNA binding motif called a DM domain, both of which regulate similar aspects of sexual development. Humandoublesex- related geneDM...
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Article
Study of a new ytterbium doped phosphate laser glass
Physical, and spectral properties of a new commercial ytterbium doped phosphate laser glass with big size, NEW/Yb, was researched. Assessing from thermal mechanical property, nonlinear property, crystalline ph...
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Article
Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms
Subcellular localization of nitric oxide (NO) synthases with effector molecules is an important regulatory mechanism for NO signalling1. In the heart, NO inhibits L-type Ca2+ channels2 but stimulates sarcoplasmic...
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Article
A common mechanism of action for three mood-stabilizing drugs
Lithium, carbamazepine and valproic acid are effective mood-stabilizing treatments for bipolar affective disorder. The molecular mechanisms underlying the actions of these drugs and the illness itself are unkn...
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Article
Functional analysis of beet necrotic yellow vein virus (BNYVV) RNA4 in fungal transmission
Full-length RNA4 of beet necrotic yellow vein virus (BNYVV) and its mutants, including a frame-shift and deletions within the coding region, were inserted into a transcription plasmid. Transcripts derived from...
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In situ localization of proteinase inhibitor mRNA in rice plant challenged by brown planthopper
Proteinase inhibitor (PI) mRNA was localized byin situ hybridization in tissue sections of root, stem and leaf of the resistant rice (B5) plant fed by brown planthopper nymphs. In the rice material without BPH fe...
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Silencing of potato virus X coat protein gene in transgenic tobaccos by codon replacement that confers resistance to PVX infection
To understand the effect of rare codon on the silencing ratio of foreign gene, some preferred codon in potato virus X (PVX) coat protein gene (cp) were substituted with synonymous rare codons. The modified PVX co...
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Article
Cloning and characterization of riceRH3 gene induced by brown planthopper
Experiments have showed that the histoneH3 gene is correlated with development, cell speciality and stress response. TheRH3 full-length cDNA was isolated from the cDNA library of rice infested by brown planthoppe...
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Expression of recombinant human lysozyme in the milk of transgenic mice
Human lysozyme is a 130-aa (amino acid) alkaline polypeptide, and has both anti-bacterial and anti-viral properties which make it an important component of human natural immunity system. As a first step toward...
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Article
Construct 2D nanostructure of co-adsorbed dipyridyl derivative by stabilization of hydrogen bond and long alkyl chains
The self-assembled structures of 4, 4′-dionoyl-2, 2′-dipyridyl and its co-adsorption with stearic acid on highly oriented pyrolytic graphite (HOPG) have been studied by the scanning tunneling microscopy (STM)....
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Article
Production of transgenic calves by somatic cell nuclear transfer
Bovine fetal oviduct epithelial cells were transfected with constructed double marker selective vector (pCE-EGFP-IRES-Neo-dNdB) containing the enhanced green fluorescent protein (EGFP) and neomycin-resistant (Neo