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Article
Synthesis, Characterization and Application of Ferrous Iron-Embedded Schwertmannite for Cr(VI) Reduction–Adsorption from Aqueous Solutions
Previous studies have demonstrated that schwertmannite (Sch) exhibits good adsorption performance for Cr(VI). In order to further enhance the ability to remove Cr(VI), this study prepared a novel composite (Fe...
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Article
Open AccessThe value of computed tomography angiography in predicting the surgical effect and prognosis of severe traumatic brain injury
It is difficult to predict the surgical effect and outcome of severe traumatic brain injury (TBI) before surgery. This study aims to approve an evaluation method of computed tomography angiography (CTA) to pre...
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Article
Open AccessFNIP1 abrogation promotes functional revascularization of ischemic skeletal muscle by driving macrophage recruitment
Ischaemia of the heart and limbs attributable to compromised blood supply is a major cause of mortality and morbidity. The mechanisms of functional angiogenesis remain poorly understood, however. Here we show ...
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Article
Open AccessControlling piezoresistance in single molecules through the isomerisation of bullvalenes
Nanoscale electro-mechanical systems (NEMS) displaying piezoresistance offer unique measurement opportunities at the sub-cellular level, in detectors and sensors, and in emerging generations of integrated elec...
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Article
Controlled Decompression Alleviates Motor Dysfunction by Regulating Microglial Polarization via the HIF-1α Signaling Pathway in Intracranial Hypertension
Decompressive craniectomy (DC) is a major form of surgery that is used to reduce intracranial hypertension (IH), the most frequent cause of death and disability following severe traumatic brain injury (sTBI) a...
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Article
Proteolytic rewiring of mitochondria by LONP1 directs cell identity switching of adipocytes
Mitochondrial proteases are emerging as key regulators of mitochondrial plasticity and acting as both protein quality surveillance and regulatory enzymes by performing highly regulated proteolytic reactions. H...
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Article
Metformin enhances neural precursor cells migration and functional recovery after ischemic stroke in mice
Resident neural precursor cells (NPCs) activation is a promising therapeutic strategy for brain repair. This strategy involves stimulating multiple stages of NPCs development, including proliferation, self-ren...
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Article
Use of deep learning-based radiomics to differentiate Parkinson’s disease patients from normal controls: a study based on [18F]FDG PET imaging
We proposed a novel deep learning–based radiomics (DLR) model to diagnose Parkinson’s disease (PD) based on [18F]fluorodeoxyglucose (FDG) PET images.
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Article
High-efficiency stabilization of lead in contaminated soil by thermal-organic acid–activated phosphate rock
Phosphate rock powder (PR) has been shown to possess the potential to stabilize lead (Pb) in soil. Most of the phosphorus (P) minerals in the world are low-grade ores, making it difficult to achieve the expect...
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Article
Open AccessATF4/CEMIP/PKCα promotes anoikis resistance by enhancing protective autophagy in prostate cancer cells
The survival of cancer cells after detaching from the extracellular matrix (ECM) is essential for the metastatic cascade. The programmed cell death after detachment is known as anoikis, acting as a metastasis ...
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Article
Open AccessCisplatin-mediated activation of glucocorticoid receptor induces platinum resistance via MAST1
Agonists of glucocorticoid receptor (GR) are frequently given to cancer patients with platinum-containing chemotherapy to reduce inflammation, but how GR influences tumor growth in response to platinum-based c...
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Article
Open AccessMetabolic network as an objective biomarker in monitoring deep brain stimulation for Parkinson’s disease: a longitudinal study
With the advance of subthalamic nucleus (STN) deep brain stimulation (DBS) in the treatment of Parkinson’s disease (PD), it is desired to identify objective criteria for the monitoring of the therapy outcome. ...
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Article
FDA-approved drug screen identifies proteasome as a synthetic lethal target in MYC-driven neuroblastoma
MYCN amplification in neuroblastoma predicts poor prognosis and resistance to therapy. Yet pharmacological strategies of direct MYC inhibition remain unsuccessful due to its “undruggable” protein structure. We he...
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Article
12-h abstinence-induced functional connectivity density changes and craving in young smokers: a resting-state study
Studying the neural correlates of craving to smoke is of great importance to improve treatment outcomes in smoking addiction. According to previous studies, the critical roles of striatum and frontal brain reg...
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Article
Enhanced lake-eutrophication model combined with a fish sub-model using a microcosm experiment
Eutrophication models are effective tools for assessing aquatic environments. The lake ecosystem consists of at least three trophic levels: phytoplankton, zooplankton, and fish. However, only a few studies hav...
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Article
Intelligent initial map scale generation based on rough-set rules
A proper initial map scale can help improve map legibility. However, the existing initial scale designs for electronic maps cannot make active adjustments according to the differences in the surrounding geogra...
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Article
Alloying Behavior and Properties of Al-Based Composites Reinforced with Al85Fe15 Metallic Glass Particles Fabricated by Mechanical Alloying and Hot Pressing Consolidation
In this study, Al85Fe15 metallic glass particles with high onset crystallization temperature (1209 K) were synthesized by a mechanical alloying method. High-quality 6061Al-based composites reinforced with Al85Fe1...
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Article
A comparative study of electroacupuncture at Zhongliao (BL33) and other acupoints for overactive bladder symptoms
Electroacupuncture (EA) at Zhongliao (BL33) can improve the symptoms of overactive bladder (OAB), such as urinary frequency, urgency, and incontinence. However, its performance compared with other acupoints re...
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Article
ESE1 is Associated with Neuronal Apoptosis in Lipopolysaccharide Induced Neuroinflammation
Neuronal apoptosis induced by the over-activation of microglia during neuroinflammation contributes to the pathology of central nervous system (CNS) degenerative diseases. ESE1 regulates apoptosis of intestina...
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Article
A case study of an enhanced eutrophication model with stoichiometric zooplankton growth sub-model calibrated by Bayesian method
Urban lakes in China have suffered from severe eutrophication over the past several years, particularly those with relatively small areas and closed watersheds. Many efforts have been made to improve the under...
