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Article
Impact of caregiving on mental, self-rated, and physical health: evidence from the China health and retirement longitudinal study
Given the escalating demand for care services, understanding the impact of informal caregiving, providing unpaid care for family members, on own health is essential. This study longitudinally analyzed the asso...
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Article
Open AccessVariation of adverse drug events in different settings in Africa: a systematic review
Adverse drug events (ADEs) represent challenges affecting Africa’s healthcare systems owing to the increased healthcare expenditure and negative health outcomes of ADEs.
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Article
Open AccessAn association study of m6A methylation with major depressive disorder
To find the relationship between N6-methyladenosine (m6A) genes and Major Depressive Disorder (MDD).
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Article
Association Between Iodine Status and Prevalence of Hypothyroidism, Autoimmune Thyroiditis, and Thyroid Nodule: a Cross-Sectional Study in Shandong Province, China
In this study, the aim was to investigate the correlation between varying levels of urinary iodine concentration (UIC) in adults and the occurrence of thyroid diseases, with the additional objective of determi...
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Article
Open AccessA two-stage hybrid ant colony algorithm for multi-depot half-open time-dependent electric vehicle routing problem
This article presents a detailed investigation into the Multi-Depot Half-Open Time-Dependent Electric Vehicle Routing Problem (MDHOTDEVRP) within the domain of urban distribution, prompted by the growing urgen...
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Article
A Cohort Study on the Effects of Maternal High Serum Iodine Status During Pregnancy on Infants in Terms of Iodine Status and Intellectual, Motor, and Physical Development
The objective of the present study was to explore the effects of maternal iodine excess during pregnancy on infants’ neurodevelopment and physical development. A total of 143 mother–child pairs were enrolled i...
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Article
Mortality following fragility hip fracture in China: a record linkage study
Mortality risk declined over time. Patients with fragility hip fracture experienced an approximate ninefold excess mortality, peaking shortly after fracture, in comparison with that of the general population. ...
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Article
Open AccessAn fNIRS investigation of novel expressed emotion stimulations in schizophrenia
Living in high expressed emotion (EE) environments tends to increase the relapse rate in schizophrenia (SZ). At present, the neural substrates responsible for high EE in SZ remain poorly understood. Functional...
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Article
Size-specific particulate matter and outpatient visits for allergic conjunctivitis in children: a time-stratified case-crossover study in Guangzhou, China
This time-stratified case-crossover study aims to quantify the risk of allergic conjunctivitis (AC) associated with short-term exposure to PMs (i.e., PM1, PM2.5, PMc, and PM10) among children in Guangzhou, China....
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Article
Trends in Adverse Drug Reactions Among Children: Evidence from Jiangsu Province of China, 2010–2019
Medication safety among children represents an underrecognized public health concern worldwide, yet little evidence was found in China. This study aimed to examine trends in rates of pediatric adverse drug rea...
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Article
What Iodine Intervention Measures Should Be Taken in Different Water Iodine Areas? Evidence from a Cross-sectional Chinese Survey
The aim of this study was to assess the population’s iodine nutrition and thyroid diseases in different water iodine areas and to offer suggestions to the governments of different countries to adjust the prese...
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Article
Exogenous Tetranectin Alleviates Pre-formed-fibrils-induced Synucleinopathies in SH-SY5Y Cells by Activating the Plasminogen Activation System
Parkinson’s disease (PD) is a common neurodegenerative disease. Previously we identified tetranectin (TN) as a differentially expressed protein in the cerebrospinal fluid of PD patients, and we were surprised ...
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Article
Study on the Effect of Different Iodine Intake on Hippocampal Metabolism in Offspring Rats
Iodine is an essential trace element in the human body. Severe maternal iodine deficiency during pregnancy leads to obvious intellectual disability in the offspring. The effects of iodine deficiency on brain d...
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Open AccessCorrection to: One hundred twelve cases of 46, XY DSD patients after initial gender assignment: a short-term survey of gender role and gender dysphoria
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Article
Identifying potential metabolic tissue biomarkers for papillary thyroid cancer in different iodine nutrient regions
To investigate the applicability of metabolomics to select thyroid cancer-associated biomarkers and discover the effects of iodine on metabolic changes in thyroid cancer.
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Article
Open AccessNutrient profiles, functional compositions, and antioxidant activities of seven types of grain fermented with Sanghuangporus sanghuang fungus
Sanghuangporus sanghuang (SS) is a rare medicinal polypore fungus that grows solely on Morus trees. In this study, seven grains (oats, barley, millet, rice, buckwheat, corn, and coix seed) were used as solid subs...
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Article
Open AccessOne hundred twelve cases of 46, XY DSD patients after initial gender assignment: a short-term survey of gender role and gender dysphoria
46, XY disorders of sex development (46, XY DSD) are congenital disorders with 46, XY chromosomal karyotype but inconsistent gonadal/phenotypic sex. One of the biggest concerns for parents and clinicians is th...
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Article
Open AccessShort-term effect of fine particulate matter and ozone on non-accidental mortality and respiratory mortality in Lishui district, China
In recent years, air pollution has become an imminent problem in China. Few studies have investigated the impact of air pollution on the mortality of the middle-aged and elderly people. Therefore, this study a...
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Article
Open AccessTemporal relationship between body mass index and uric acid and their joint impact on blood pressure in children and adults: the Bogalusa Heart Study
This study aimed to examine the temporal relationship between body mass index (BMI) and uric acid (UA), and their joint effect on blood pressure (BP) in children and adults.
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Article
Open AccessDNA methylation data-based molecular subtype classification and prediction in patients with gastric cancer
Genetic and epigenetic alterations have been indicated to be closely correlated with the carcinogenesis, DNA methylation is one of most frequently occurring molecular behavior that take place early during this...
