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  1. Article

    Open Access

    Non-destructive testing of interfacial stiffness based on spring model for diffusion bonding interface of titanium alloy components with complex surface

    Ultrasonic testing is an important non-destructive testing method, which is sensitive to the defects in the diffusion bonding interface. Ultrasonic testing of diffusion bonding interfaces in complex-surface co...

    Gongpeng Yang, Zhenggan Zhou, Tengfei Ma, Lichen Teng, Jun Wang in Scientific Reports (2023)

  2. Article

    Open Access

    Initial experience with surrounding en bloc transurethral resection of bladder tumor and simultaneous intravesical treating for non-muscle invasive bladder cancer

    The high recurrence rate after traditional transurethral resection of bladder tumor (TURBT) remains a challenge for management of non-muscle invasive bladder tumor (NMIBC). The aim of this study was to evaluat...

    Lichen Teng, Changfu Li, Wentao Wang, Dechao Li in BMC Urology (2022)

  3. Article

    Open Access

    A novel non-destructive testing method for turbine disks using dual array ultrasonic transducer

    A novel dual array inspection method for detecting the diffusion bonding defects of superalloy turbine disk has been proposed in this study. The influence of relative position between the planar defect and aco...

    Lichen Teng, Zhenggan Zhou in Scientific Reports (2022)

  4. Article

    Open Access

    Articular and Extra-Articular Benefits in ACR20 Non-responders at Week 104 Treated With Apremilast: Pooled Analysis of Three Randomized Controlled Trials

    PALACE 1, 2, and 3 were phase 3 studies aimed to evaluate apremilast efficacy and safety in patients with active psoriatic arthritis (PsA) despite prior treatment with conventional disease-modifying anti-rheum...

    Philip J. Mease, Dafna D. Gladman, Arthur Kavanaugh in Rheumatology and Therapy (2021)

  5. Article

    Open Access

    LncRNA HOTAIR induces sunitinib resistance in renal cancer by acting as a competing endogenous RNA to regulate autophagy of renal cells

    Cell autophagy has been proposed to be involved in drug resistance therapy. However, how the long non-coding RNA (lncRNA) reduces risks of drug resistance in renal cancer (RC) cells needs a thorough inquiry. T...

    Dechao Li, Changfu Li, Yongsheng Chen, Lichen Teng, Yan Cao in Cancer Cell International (2020)

  6. Article

    Open Access

    Long-term experience with apremilast in patients with psoriatic arthritis: 5-year results from a PALACE 1–3 pooled analysis

    The efficacy and safety of apremilast were assessed in patients with psoriatic arthritis (PsA) in three phase III clinical trials with similar designs (PALACE 1, 2, and 3).

    Arthur Kavanaugh, Dafna D. Gladman, Christopher J. Edwards in Arthritis Research & Therapy (2019)

  7. Article

    Open Access

    Identification of biological targets of therapeutic intervention for clear cell renal cell carcinoma based on bioinformatics approach

    We aimed to discover the potential microRNA (miRNA) targets and to explore the underlying molecular mechanisms of clear cell renal cell carcinoma (ccRCC).

    Yongsheng Chen, Lichen Teng, Wenhua Liu, Yan Cao, Dexin Ding in Cancer Cell International (2016)

  8. Article

    Open Access

    Anti-tumor effect of ribavirin in combination with interferon-α on renal cell carcinoma cell lines in vitro

    Ribavirin is an anti-viral drug; however, recent data suggest that it may also be effective in cancer therapy. This study investigated the effect of ribavirin alone or in combination with IFN-α on biological p...

    Lichen Teng, Dexin Ding, Yongsheng Chen, Hongshuang Dai in Cancer Cell International (2014)

  9. No Access

    Article

    Immunosuppressive effect of renal cell carcinoma on phenotype and function of dendritic cells

    Dendritic cells (DCs) play an important role in anti-renal cell carcinoma (RCC) immunity. The aim of the study was to investigate effect of mimic RCC microenvironment on phenotype and function of DCs. We isola...

    Lichen Teng, Yongsheng Chen, Dexin Ding in International Urology and Nephrology (2014)

  10. Article

    Open Access

    Id1 enhances human ovarian cancer endothelial progenitor cell angiogenesis via PI3K/Akt and NF-κB/MMP-2 signaling pathways

    Endothelial progenitor cells (EPCs) contribute to tumor angiogenesis and growth. We previously reported that over-expression of an inhibitor of DNA binding/differentiation 1 (Id1) in EPCs can enhance EPC proli...

    Yajuan Su, Lingjuan Gao, Lichen Teng, Ying Wang in Journal of Translational Medicine (2013)

  11. No Access

    Article

    Application of Dual Radiotelemetric Technique in Studying Drug–Drug Interaction Between Diclofenac Sodium and Ranitidine HCl in Volunteers

    Drug–drug interaction between a commercial diclofenac sodium enteric-coated tablet (Voltaren; V) and a ranitidine HCI tablet (Zantac; Z) was evaluated using a dual radiotelemetric technique according to a rand...

    Catherine Alioth, Robert A. Blum, David T. D'Andrea in Pharmaceutical Research (1993)