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  1. Article

    Open Access

    LncRNA HOTAIR induces sunitinib resistance in renal cancer by acting as a competing endogenous RNA to regulate autophagy of renal cells

    Cell autophagy has been proposed to be involved in drug resistance therapy. However, how the long non-coding RNA (lncRNA) reduces risks of drug resistance in renal cancer (RC) cells needs a thorough inquiry. T...

    Dechao Li, Changfu Li, Yongsheng Chen, Lichen Teng, Yan Cao in Cancer Cell International (2020)

  2. Article

    Open Access

    Identification of biological targets of therapeutic intervention for clear cell renal cell carcinoma based on bioinformatics approach

    We aimed to discover the potential microRNA (miRNA) targets and to explore the underlying molecular mechanisms of clear cell renal cell carcinoma (ccRCC).

    Yongsheng Chen, Lichen Teng, Wenhua Liu, Yan Cao, Dexin Ding in Cancer Cell International (2016)

  3. Article

    Open Access

    Anti-tumor effect of ribavirin in combination with interferon-α on renal cell carcinoma cell lines in vitro

    Ribavirin is an anti-viral drug; however, recent data suggest that it may also be effective in cancer therapy. This study investigated the effect of ribavirin alone or in combination with IFN-α on biological p...

    Lichen Teng, Dexin Ding, Yongsheng Chen, Hongshuang Dai in Cancer Cell International (2014)

  4. Article

    Open Access

    Id1 enhances human ovarian cancer endothelial progenitor cell angiogenesis via PI3K/Akt and NF-κB/MMP-2 signaling pathways

    Endothelial progenitor cells (EPCs) contribute to tumor angiogenesis and growth. We previously reported that over-expression of an inhibitor of DNA binding/differentiation 1 (Id1) in EPCs can enhance EPC proli...

    Yajuan Su, Lingjuan Gao, Lichen Teng, Ying Wang in Journal of Translational Medicine (2013)

  5. No Access

    Article

    Application of Dual Radiotelemetric Technique in Studying Drug–Drug Interaction Between Diclofenac Sodium and Ranitidine HCl in Volunteers

    Drug–drug interaction between a commercial diclofenac sodium enteric-coated tablet (Voltaren; V) and a ranitidine HCI tablet (Zantac; Z) was evaluated using a dual radiotelemetric technique according to a rand...

    Catherine Alioth, Robert A. Blum, David T. D'Andrea in Pharmaceutical Research (1993)