1,449 Result(s)
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Lian-**ang **ao
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Open AccessSimultaneous bilateral video-assisted thoracic surgery is safe and feasible for multiple primary lung cancers
The treatment for bilateral synchronous multiple primary lung cancers (MPLC) remains challenging. Simultaneous bilateral video-assisted thoracic surgery (VATS) may be an optimal treatment with curative intent,...
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Open AccessSearch for the \( {B}_s^0 \) → μ+μ−γ decay
A search for the fully reconstructed B s 0 ...
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Open AccessSynthetic macrolides overcoming MLSBK-resistant pathogens
Conventional macrolide-lincosamide-streptogramin B-ketolide (MLSBK) antibiotics are unable to counter the growing challenge of antibiotic resistance that is conferred by the constitutive methylation of rRNA base ...
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Open AccessEnhanced recombination empowers the detection and map** of Quantitative Trait Loci
Modern plant breeding, such as genomic selection and gene editing, is based on the knowledge of the genetic architecture of desired traits. Quantitative trait loci (QTL) analysis, which combines high throughpu...
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Open AccessCultivation of novel Atribacterota from oil well provides new insight into their diversity, ecology, and evolution in anoxic, carbon-rich environments
The Atribacterota are widely distributed in the subsurface biosphere. Recently, the first Atribacterota isolate was described and the number of Atribacterota genome sequences retrieved from environmental samples ...
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Open AccessRapid identification of early infections in febrile patients after CD19 target CAR-T cell therapy for B-cell malignancies
CD19-targeted chimeric antigen receptor T (CAR-T) cell therapy stands out as a revolutionary intervention, exhibiting remarkable remission rates in patients with refractory/relapsed (R/R) B-cell malignancies. ...
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Open AccessIn a rat model of bypass DuraGraft ameliorates endothelial dysfunction of arterial grafts
Coronary artery bypass surgery can result in endothelial dysfunction due to ischemia/reperfusion (IR) injury. Previous studies have demonstrated that DuraGraft helps maintain endothelial integrity of saphenous...
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Open AccessFacile synthesis of elastin nanogels encapsulated decursin for castrated resistance prostate cancer therapy
Nanogels offer hope for precise drug delivery, while addressing drug delivery hurdles is vital for effective prostate cancer (PCa) management. We developed an injectable elastin nanogels (ENG) for efficient dr...
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Correction to: Efficacy and Safety of Neoadjuvant Subcutaneous Envafolimab in dMMR/MSI-H Locally Advanced Colon Cancer
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Open AccessPEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3
The peroxisome is a versatile organelle that performs diverse metabolic functions. PEX3, a critical regulator of the peroxisome, participates in various biological processes associated with the peroxisome. Whe...
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Open AccessOptimal dichotomization of bimodal Gaussian mixtures
Despite criticism for loss of information and power, dichotomization of variables is still frequently used in social, behavioral, and medical sciences, mainly because it yields more interpretable conclusions f...
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Open AccessWhen large language models meet personalization: perspectives of challenges and opportunities
The advent of large language models marks a revolutionary breakthrough in artificial intelligence. With the unprecedented scale of training and model parameters, the capability of large language models has bee...
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Open AccessNicotinate-curcumin improves NASH by inhibiting the AKR1B10/ACCα-mediated triglyceride synthesis
Nonalcoholic steatohepatitis (NASH) is a prevalent chronic liver condition. However, the potential therapeutic benefits and underlying mechanism of nicotinate-curcumin (NC) in the treatment of NASH remain unce...
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Open AccessCharacterization of the DNA accessibility of chloroplast genomes in grasses
Although the chloroplast genome (cpDNA) of higher plants is known to exist as a large protein-DNA complex called ‘plastid nucleoid’, researches on its DNA state and regulatory elements are limited. In this stu...
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Correction: Improved Indian Summer Monsoon rainfall simulation: the significance of reassessing the autoconversion parameterization in coupled climate model
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Open AccessNovel radiopaque ethanol injection: physicochemical properties, animal experiments, and clinical application in vascular malformations
Despite the efficacy of absolute ethanol (EtOH), its radiolucency introduces several risks in interventional therapy for treating vascular malformations. This study aims to develop a novel radiopaque ethanol i...
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Open AccessFractal analysis of left ventricular trabeculae in heart failure with preserved ejection fraction patients with multivessel coronary artery disease
Endocardial trabeculae undergo varicose changes and hyperplasia in response to hemodynamic influences and are a variable phenotype reflecting changes in disease. Fractal analysis has been used to analyze the c...
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Open AccessHaplotype-resolved assembly of a pig genome using single-sperm sequencing
Single gamete cell sequencing together with long-read sequencing can reliably produce chromosome-level phased genomes. In this study, we employed PacBio HiFi and Hi-C sequencing on a male Landrace pig, coupled...
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Open AccessMicrogels for Cell Delivery in Tissue Engineering and Regenerative Medicine
This review provides a comprehensive summary associated with recent progress in the preparation and application of microgels.
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Open AccessExploring prognostic values of DNA ploidy, stroma-tumor fraction and nucleoty** in stage II colon cancer patients
To assess the prognostic value of three novel biomarkers, DNA ploidy, stroma-tumor fraction, and nucleoty**, seeking for more accurate stratification in stage II colon cancer.
