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Article
Open AccessSingle-cell RNA sequencing explores the evolution of the ecosystem from leukoplakia to head and neck squamous cell carcinoma
It has been found that progression from leukoplakia to head and neck squamous cell carcinoma (HNSCC) is a long-term process that may involve changes in the multicellular ecosystem. We acquired scRNA-seq sample...
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Article
Open AccessEffect of radiotherapy on head and neck cancer tissues in patients receiving radiotherapy: a bioinformatics analysis-based study
Radiotherapy is pivotal in treating head and neck cancers including nasopharyngeal, tongue, hypopharyngeal, larynx, maxillary sinus, parotid gland, and oral cancers. It holds the potential for curative effects...
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Article
Open AccessRole of m6A modification in regulating the PI3K/AKT signaling pathway in cancer
The phosphoinositide 3-kinase (PI3K)/AKT signaling pathway plays a crucial role in the pathogenesis of cancer. The dysregulation of this pathway has been linked to the development and initiation of various typ...
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Article
Open Accessm6A RNA methylation regulator-related signatures exhibit good prognosis prediction ability for head and neck squamous cell carcinoma
Head and neck squamous cell carcinoma (HNSCC) has become the sixth most common malignant disease worldwide and is associated with high mortality, with an overall 5-year survival rate of less than 50%. Recent s...
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Article
Open AccessConstruction of a hypoxia-derived gene model to predict the prognosis and therapeutic response of head and neck squamous cell carcinoma
Head and neck squamous cell carcinoma (HNSCC) ranks as the sixth most common cancer worldwide and has a poor prognosis in the advanced stage. Increasing evidence has shown that hypoxia contributes to genetic a...
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Article
Open AccessBioinformatics analysis of DNMT1 expression and its role in head and neck squamous cell carcinoma prognosis
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common type of malignancy in the world. DNA cytosine-5-methyltransferase 1 (DNMT1) play key roles in carcinogenesis and regulation of the immune ...
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Article
Effects of Chronic Ephedrine Toxicity on Functional Connections, Cell Apoptosis, and CREB-Related Proteins in the Prefrontal Cortex of Rhesus Monkeys
Ephedrine abuse has spread in many parts of the world, severely threatening human health. The mechanism of ephedrine toxicity is still unclear. To explore the possible neural mechanisms of ephedrine toxicity, ...
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Article
Open AccessNewtonian flow inside carbon nanotube with permeable boundary taking into account van der Waals forces
Here, water flow inside large radii semi-infinite carbon nanotubes is investigated. Permeable wall taking into account the molecular interactions between water and a nanotube, and the slip boundary condition w...
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Article
Open AccessA double projection algorithm for quasimonotone variational inequalities in Banach spaces
We propose a double projection algorithm for solving variational inequality problems in Banach spaces. We establish the strong convergence of the whole sequence generated by the proposed method under the quasi...
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Article
Open AccessThe subgradient double projection method for variational inequalities in a Hilbert space
We present a modification of the double projection algorithm proposed by Solodov and Svaiter for solving variational inequalities (VI) in a Hilbert space. The main modification is to use the subgradient of a c...
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Article
Open AccessA superlinearly convergent hybrid algorithm for systems of nonlinear equations
We propose a new algorithm for solving systems of nonlinear equations with convex constraints which combines elements of Newton, the proximal point, and the projection method. The convergence of the whole sequ...
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Chapter and Conference Paper
A Neighborhood Incorporated Method in Image Registration
Mutual information has been widely used in image registration as an effective similarity measure. It has attracted a lot of attention to the effective use of the spatial information. Here we propose a new meas...
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Protocol
Stimulation of Anti-HIV-1 Cytotoxic T Lymphocytes by Dendritic Cells
Dendritic cells (DC) are highly specialized antigen-presenting cells (APC) in both primary and secondary T-cell responses. This may be related to their expression of high levels of MHC class I and II antigens (1-
