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Article
Trends in urinary stone composition in 23,182 stone analyses from 2011 to 2019: a high-volume center study in China
To evaluate the distribution and dynamic trends in constituents of urinary stones in China.
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Article
1H NMR-based metabolomic study of metabolic profiling for the urine of kidney stone patients
Kidney stone is a chronic metabolic disease that caused by many factors, especially by the metabolic disturbances of urine compositions, but the metabolic profiling of the urine from kidney stone patients rema...
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Article
Predictors for uroseptic shock in patients who undergo minimally invasive percutaneous nephrolithotomy
To identify risk factors that can predict which patient is likely to progress from systemic inflammatory response syndrome (SIRS) to uroseptic shock after minimally invasive percutaneous nephrolithotomy (MPCNL...
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Article
Difference in urinary stone composition between Uyghur and Han children with urolithiasis
The Objective of this study is to analyze the difference in renal stone composition between Uyghur and Han children with urolithiasis in China and possible reasons. From May 2011 to September 2013, we analyzed...
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Article
Metabolic disturbances in Chinese children with urolithiasis: a single center report
Urinary stones and urine composition are the first steps in the process of recurrence prevention, but data concerning the association between the two compositions are scarce in Chinese children with urolithias...
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Article
Association study of DGKH gene polymorphisms with calcium oxalate stone in Chinese population
Diacylglycerol kinase eta (DGKH) participates in regulating the intracellular concentrations of two bioactive lipids, diacylglycerol and phosphatidic acid. With the emerging evidence of a novel regulatory func...
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Article
Synthesis and biological evaluation of 1-cyano-2-amino-benzimidazole derivatives as a novel class of antitumor agents
A series of 1-cyano-2-amino-benzimidazole derivatives were synthesized and evaluated for their cytotoxic activities in vitro against three human cancer cell lines (human lung carcinoma cell line: A549, human l...
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Article
Urinary stone analysis on 12,846 patients: a report from a single center in China
We reported a retrospective review of the urinary stone compositions in 12,846 patients. Data on urinary stone compositions analyzed between January 2003 and December 2012 in our center were collected. Infrare...
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Article
Parallel synthesis of novel antitumor agents: 1,2,3-triazoles bearing biologically active sulfonamide moiety and their 3D-QSAR
A 60-member 1,2,3-triazoles bearing biologically active sulfonamide moiety library was synthesized via azide–alkyne cycloaddition and examined for cytotoxic activity against human leukemia cell line HL-60. 25 ...
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Article
Design, synthesis and 3D-QSAR study of cytotoxic flavonoid derivatives
Three series of flavonoid derivatives were designed and synthesized. All synthesized compounds were evaluated for cytotoxic activities against five human cancer cell lines, including K562, PC-3, MCF-7, A549, a...