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Article
Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBi**g, a Chinese herb-based intravenous formulation
Sepsis, a life-threatening health issue, lacks effective medicine targeting the septic response. In China, treatment combining the intravenous herbal medicine XueBi**g with conventional procedures reduces the...
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Article
Characteristics of circRNAs expression profiles in the piglets intestine induced by oxidative stress
Oxidative stress (OS) can affect the expression of key genes and destroy the intestinal structure. However, it is unclear how OS regulates the expression of circular RNAs (circRNAs), microRNAs (miRNAs) and mRNAs.
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Article
Open AccessSestrin2 protects against lethal sepsis by suppressing the pyroptosis of dendritic cells
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Sestrin2 (SESN2), a highly evolutionarily conserved protein, is critically involved in the cellular ...
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Article
Open AccessSestrin2 protects dendrite cells against ferroptosis induced by sepsis
Ferroptosis is a nonapoptotic form of programmed cell death triggered by the accumulation of reactive oxygen species (ROS) depended on iron overload. Although most investigations focus on the relationship betw...
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Article
Open AccessSestrin2 protects dendritic cells against endoplasmic reticulum stress-related apoptosis induced by high mobility group box-1 protein
Sestrin2 (SESN2) is a highly evolutionary conserved protein and involved in different cellular responses to various stresses. However, the potential function of SESN2 in immune system remains unclear. The pres...
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Article
Open AccessComparative evaluation of epidural bupivacaine alone and bupivacaine combined with magnesium sulfate in providing postoperative analgesia: a meta-analysis of randomized controlled trials
The comparative efficacy of epidural bupivacaine alone and bupivacaine combined with magnesium sulfate in providing postoperative analgesia remains controversial.
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Article
Wave Attenuation Performance and the Influencing Factors of A Lower Arc-Plate Breakwater
Comprehensive experimental and numerical studies have been undertaken to investigate wave energy dissipation performance and main influencing factors of a lower arc-plate breakwater. The numerical model, which...
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Article
Historical introduction, geographical distribution, and biological characteristics of alien plants in China
Using the published literature and records, this study investigated the historical introduction, geographical distribution, and biological characteristics of 404 alien plants in 32 provinces (including municip...
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Article
Glutamate Transporters/Na+, K+-ATPase Involving in the Neuroprotective Effect as a Potential Regulatory Target of Glutamate Uptake
The glutamate (Glu) transporters GLAST and GLT-1, as the two most important transporters in brain tissue, transport Glu from the extracellular space into the cell protecting against Glu toxicity. Furthermore, ...
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Article
Open AccessSynthesis of novel galactose functionalized gold nanoparticles and its radiosensitizing mechanism
Biocompatible gold nanoparticles (GNPs) are potentially practical and efficient agents in cancer radiotherapy applications. In this study, we demonstrated that GNPs can significantly modulate irradiation respo...
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Article
Allelopathic potential of Artemisia frigida and successional changes of plant communities in the northern China steppe
In the northern China steppe, overgrazing has decreased the abundance of many species that were originally dominant, but increased the abundance of Artemisia frigida. We aimed to determine whether the adaptive an...
