Skip to main content

3 Result(s)

within Li-Li Ji Remove this filter Biomedicine, general Remove this filter Vaccine Remove this filter

and

  1. No Access

    Article

    Isotoosendanin inhibits triple-negative breast cancer metastasis by reducing mitochondrial fission and lamellipodia formation regulated by the Smad2/3-GOT2-MYH9 signaling axis

    Triple-negative breast cancer (TNBC) is incurable and prone to widespread metastasis. Therefore, identification of key targets for TNBC progression is urgently needed. Our previous study revealed that isotoose...

    **g-nan Zhang, Ze Zhang, Zhen-lin Huang, Qian Guo, Ze-qi Wu… in Acta Pharmacologica Sinica (2024)

  2. No Access

    Article

    Scutellarin suppresses triple-negative breast cancer metastasis by inhibiting TNFα-induced vascular endothelial barrier breakdown

    Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with high vascularity and frequent metastasis. Tumor-associated abnormal vasculature was reported to accelerate TNBC metastasis. S...

    **-yu Mei, **g-nan Zhang, Wang-ya Jia, Bin Lu, Meng-na Wang… in Acta Pharmacologica Sinica (2022)

  3. No Access

    Article

    Quercetin attenuates toosendanin-induced hepatotoxicity through inducing the Nrf2/GCL/GSH antioxidant signaling pathway

    Toosendanin (TSN) is the main active compound in Toosendan Fructus and Meliae Cortex, two commonly used traditional Chinese medicines. TSN has been reported to induce hepatotoxicity, but its mechanism remains ...

    Yao **, Zhen-lin Huang, Li Li, Yang Yang, Chang-hong Wang… in Acta Pharmacologica Sinica (2019)