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Article
miR-375-3p targets YWHAB to attenuate intestine injury in neonatal necrotizing enterocolitis
Necrotizing enterocolitis (NEC) is a significant contributor to neonatal mortality. This study aimed to investigate the role of high levels of miR-375-3p in breast milk in the development of NEC and elucidate ...
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Article
Open AccessIntegrated machine learning-driven disulfidptosis profiling: CYFIP1 and EMILIN1 as therapeutic nodes in neuroblastoma
Neuroblastoma (NB), a prevalent pediatric solid tumor, presents formidable challenges due to its high malignancy and intricate pathogenesis. The role of disulfidptosis, a novel form of programmed cell death, r...
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Chapter and Conference Paper
Critical Technologies for UAV Swarm Collaborative Mission Planning
This paper delves into the pivotal technologies of cooperative mission planning of Unmanned Aerial Vehicle (UAV) swarms, encompassing collaborative control technology, task allocation and path planning technol...
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Article
Circular RNA MTCL1 targets SMAD3 by sponging miR-145‐5p for regulation of cell proliferation and migration in Hirschsprung’s disease
Hirschsprung’s disease (HSCR) is a congenital disorder resulting from abnormal development of the enteric nervous system (ENS). Given the complexity of its pathogenesis, it is important to investigate the role...
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Article
Preoperative embolization is necessary for large-volume carotid body tumor (≥ 6670 mm3) resection
To investigate the impact of preoperative embolization (p-TAE) on CBT surgical resection and explore the optimal tumor volume for p-TAE of CBT resection.
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Article
A new extended finite element model for gas flow in shale gas reservoirs with complex fracture networks
The key factors to the success of shale gas play are complex fracture network and stimulated reservoir volume (SRV) after the treatment of massive hydraulic fracturing. These two factors jointly determine the ...
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Article
Open AccessInhibitory effects of Camellia japonica on cell inflammation and acute rat reflux esophagitis
Excessive and continuous inflammation may be the main cause of various immune system diseases. Reflux esophagitis (RE) is a common gastroesophageal reflux disease (GERD). Camellia japonica has high medicinal valu...
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Chapter and Conference Paper
Intelligent Mobile Communication Network Plan for 5G Based on Insight Big Data
Traditional mobile communication network plan depends on simple data analysis and manual judgment, which is easily influenced by the personal experience and ability. To fully use the data and avoid manual err...
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Article
Open AccessCostunolide inhibits inflammation in LPS-induced RAW264.7 cells and ameliorates gastric acid reflux-induced esophageal injury in rat model
As one of the gastroesophageal reflux disease (GERD), reflux esophagitis (RE) severely affects patients’ daily lives. Costunolide (Cos), pertains to a sesquiterpene lactone, performs multiple pharmacological a...
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Article
Open AccessAccuracy of intraocular lens power calculation formulae after laser refractive surgery in myopic eyes: a meta-analysis
To compare the accuracy of intraocular lens power calculation formulae after laser refractive surgery in myopic eyes.
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Article
Safety and efficacy of oncolytic HSV-1 G207 inoculated into the cerebellum of mice
Primary malignant central nervous system (CNS) tumors are the leading cause of childhood cancer-related death and morbidity. While advances in surgery, radiation, and chemotherapy have improved the survival ra...
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Article
Open AccessGeraniin ameliorate experimental acute reflux esophagitis via NF-κB regulated anti-inflammatory activities in rats
Repeated reflux of gastric acid and stomach contents into the esophagus leads to esophagus damage, including inflammation, ulcer, and hemorrhage in the epithelium. In this study, we aimed to demonstrate the am...
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Article
UAB30, a novel RXR agonist, decreases tumorigenesis and leptomeningeal disease in group 3 medulloblastoma patient-derived xenografts
Group 3 tumors account for approximately 25–30% of medulloblastomas and have the worst prognosis. UAB30 is a novel synthetic rexinoid shown to have limited toxicities in humans and significant efficacy in the ...
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Article
Open AccessEnhanced Sensitivity of Patient-Derived Pediatric High-Grade Brain Tumor Xenografts to Oncolytic HSV-1 Virotherapy Correlates with Nectin-1 Expression
Pediatric high-grade brain tumors and adult glioblastoma are associated with significant morbidity and mortality. Oncolytic herpes simplex virus-1 (oHSV) is a promising approach to target brain tumors; oHSV G2...
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Article
Open AccessClinical and Immunological Effects of rhIL-2 Therapy in Eastern Chinese Patients with Multidrug-resistant Tuberculosis
It is urgent to find an optimised therapy regimen for the control of MDR-TB globally. This study aimed to evaluate the efficiacy and safety of a combined regimen of rhIL-2 injection and standard chemotherapy w...
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Article
Open AccessRetrospective analysis of population-based causes of death and life expectancy in urban Western China from 2003 to 2012
Hitherto, a population-based analysis of the cause of death in urban areas of Western China has not been undertaken over an extended period. The aims of this study were to calculate the overall and annual caus...
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Article
Open AccessAn advanced fragment analysis-based individualized subtype classification of pediatric acute lymphoblastic leukemia
Pediatric acute lymphoblastic leukemia (ALL) is the most common neoplasm and one of the primary causes of death in children. Its treatment is highly dependent on the correct classification of subtype. Previous...
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Chapter and Conference Paper
A Correlative Research on the Relationship Between Awareness in Collaborative Learning and its Impact on Academic Performance
In the collaborative learning environment, the learners will produce certain awareness within the group based on all kinds of relevant information, that is, collaborative-learning awareness. Through survey met...
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Chapter
A Strategic and Emotional Partner: China and Its Food Aid to North Korea in the Twenty-First Century
In China and North Korea, natural disasters have long been popularly understood to portend dynastic transitions and, more recently, regime changes. Even today, environmental catastrophes can raise doubts as to...
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Chapter and Conference Paper
Application Study of Spatiotemporal Chaotic Sequence in Code Division Multiple Access Communication System
This paper presents a design plan of spatiotemporal chaos system based on the coupled map lattice model, studies the spatiotemporal chaotic sequence of balance, relevance and complexity generated by the model,...