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  1. No Access

    Article

    miR-375-3p targets YWHAB to attenuate intestine injury in neonatal necrotizing enterocolitis

    Necrotizing enterocolitis (NEC) is a significant contributor to neonatal mortality. This study aimed to investigate the role of high levels of miR-375-3p in breast milk in the development of NEC and elucidate ...

    Li Nan, Fan Kaisi, Zhang Mengzhen, Yang Yang in Pediatric Surgery International (2024)

  2. Article

    Open Access

    Integrated machine learning-driven disulfidptosis profiling: CYFIP1 and EMILIN1 as therapeutic nodes in neuroblastoma

    Neuroblastoma (NB), a prevalent pediatric solid tumor, presents formidable challenges due to its high malignancy and intricate pathogenesis. The role of disulfidptosis, a novel form of programmed cell death, r...

    Zhang Mengzhen, Hou **nwei, Tan Zeheng in Journal of Cancer Research and Clinical On… (2024)

  3. No Access

    Chapter and Conference Paper

    Critical Technologies for UAV Swarm Collaborative Mission Planning

    This paper delves into the pivotal technologies of cooperative mission planning of Unmanned Aerial Vehicle (UAV) swarms, encompassing collaborative control technology, task allocation and path planning technol...

    Sun Yu, Yin Ranran, Li Nan in Proceedings of 2023 11th China Conference … (2024)

  4. No Access

    Article

    Circular RNA MTCL1 targets SMAD3 by sponging miR-145‐5p for regulation of cell proliferation and migration in Hirschsprung’s disease

    Hirschsprung’s disease (HSCR) is a congenital disorder resulting from abnormal development of the enteric nervous system (ENS). Given the complexity of its pathogenesis, it is important to investigate the role...

    Wang Chen, Luo Caiyun, Yang Yang, Hou **nwei, Li Nan in Pediatric Surgery International (2023)

  5. No Access

    Article

    Preoperative embolization is necessary for large-volume carotid body tumor (≥ 6670 mm3) resection

    To investigate the impact of preoperative embolization (p-TAE) on CBT surgical resection and explore the optimal tumor volume for p-TAE of CBT resection.

    Li Nan, Yang Ruimeng, Chang Guangqi in European Archives of Oto-Rhino-Laryngology (2023)

  6. No Access

    Article

    A new extended finite element model for gas flow in shale gas reservoirs with complex fracture networks

    The key factors to the success of shale gas play are complex fracture network and stimulated reservoir volume (SRV) after the treatment of massive hydraulic fracturing. These two factors jointly determine the ...

    Li Nan, Yang Kang, Kao Jiawei in Arabian Journal of Geosciences (2023)

  7. Article

    Open Access

    Inhibitory effects of Camellia japonica on cell inflammation and acute rat reflux esophagitis

    Excessive and continuous inflammation may be the main cause of various immune system diseases. Reflux esophagitis (RE) is a common gastroesophageal reflux disease (GERD). Camellia japonica has high medicinal valu...

    Hyeon Hwa Nam, Li Nan, Byung Kil Choo in Chinese Medicine (2021)

  8. No Access

    Chapter and Conference Paper

    Intelligent Mobile Communication Network Plan for 5G Based on Insight Big Data

    Traditional mobile communication network plan depends on simple data analysis and manual judgment, which is easily influenced by the personal experience and ability. To fully use the data and avoid manual err...

    Cao Guang Shan, Zhang Jian Ming, Hao Xue Yi in Signal and Information Processing, Network… (2021)

  9. Article

    Open Access

    Costunolide inhibits inflammation in LPS-induced RAW264.7 cells and ameliorates gastric acid reflux-induced esophageal injury in rat model

    As one of the gastroesophageal reflux disease (GERD), reflux esophagitis (RE) severely affects patients’ daily lives. Costunolide (Cos), pertains to a sesquiterpene lactone, performs multiple pharmacological a...

    Li Nan, Hyeon-Hwa Nam, Byung-Kil Choo in Applied Biological Chemistry (2020)

  10. Article

    Open Access

    Accuracy of intraocular lens power calculation formulae after laser refractive surgery in myopic eyes: a meta-analysis

    To compare the accuracy of intraocular lens power calculation formulae after laser refractive surgery in myopic eyes.

    Hongyu Li, Li Nan, Jun Li, Hui Song in Eye and Vision (2020)

  11. No Access

    Article

    Safety and efficacy of oncolytic HSV-1 G207 inoculated into the cerebellum of mice

    Primary malignant central nervous system (CNS) tumors are the leading cause of childhood cancer-related death and morbidity. While advances in surgery, radiation, and chemotherapy have improved the survival ra...

    Joshua D. Bernstock, Nunzio Vicario, Rong Li, Li Nan in Cancer Gene Therapy (2020)

  12. Article

    Open Access

    Geraniin ameliorate experimental acute reflux esophagitis via NF-κB regulated anti-inflammatory activities in rats

    Repeated reflux of gastric acid and stomach contents into the esophagus leads to esophagus damage, including inflammation, ulcer, and hemorrhage in the epithelium. In this study, we aimed to demonstrate the am...

    Hyeon Hwa Nam, Li Nan, ** Cheon Park, Byung Kil Choo in Applied Biological Chemistry (2019)

  13. No Access

    Article

    UAB30, a novel RXR agonist, decreases tumorigenesis and leptomeningeal disease in group 3 medulloblastoma patient-derived xenografts

    Group 3 tumors account for approximately 25–30% of medulloblastomas and have the worst prognosis. UAB30 is a novel synthetic rexinoid shown to have limited toxicities in humans and significant efficacy in the ...

    Evan F. Garner, Laura L. Stafman, Adele P. Williams in Journal of Neuro-Oncology (2018)

  14. Article

    Open Access

    Enhanced Sensitivity of Patient-Derived Pediatric High-Grade Brain Tumor Xenografts to Oncolytic HSV-1 Virotherapy Correlates with Nectin-1 Expression

    Pediatric high-grade brain tumors and adult glioblastoma are associated with significant morbidity and mortality. Oncolytic herpes simplex virus-1 (oHSV) is a promising approach to target brain tumors; oHSV G2...

    Gregory K. Friedman, Joshua D. Bernstock, Dongquan Chen, Li Nan in Scientific Reports (2018)

  15. Article

    Open Access

    Clinical and Immunological Effects of rhIL-2 Therapy in Eastern Chinese Patients with Multidrug-resistant Tuberculosis

    It is urgent to find an optimised therapy regimen for the control of MDR-TB globally. This study aimed to evaluate the efficiacy and safety of a combined regimen of rhIL-2 injection and standard chemotherapy w...

    Qi Tan, Rui Min, Guan-qun Dai, Yan-li Wang, Li Nan, Zhen Yang in Scientific Reports (2017)

  16. Article

    Open Access

    Retrospective analysis of population-based causes of death and life expectancy in urban Western China from 2003 to 2012

    Hitherto, a population-based analysis of the cause of death in urban areas of Western China has not been undertaken over an extended period. The aims of this study were to calculate the overall and annual caus...

    Deng Shi-min, Rong Shun-kang, Yao Yuan-qing, Qian Jun, Huang **g in BMC Public Health (2016)

  17. Article

    Open Access

    An advanced fragment analysis-based individualized subtype classification of pediatric acute lymphoblastic leukemia

    Pediatric acute lymphoblastic leukemia (ALL) is the most common neoplasm and one of the primary causes of death in children. Its treatment is highly dependent on the correct classification of subtype. Previous...

    Han Zhang, Hao Cheng, Qingqing Wang, ** Zeng, Yanfen Chen in Scientific Reports (2015)

  18. No Access

    Chapter and Conference Paper

    A Correlative Research on the Relationship Between Awareness in Collaborative Learning and its Impact on Academic Performance

    In the collaborative learning environment, the learners will produce certain awareness within the group based on all kinds of relevant information, that is, collaborative-learning awareness. Through survey met...

    Zhong Keding, Li Nan in Emerging Issues in Smart Learning (2015)

  19. No Access

    Chapter

    A Strategic and Emotional Partner: China and Its Food Aid to North Korea in the Twenty-First Century

    In China and North Korea, natural disasters have long been popularly understood to portend dynastic transitions and, more recently, regime changes. Even today, environmental catastrophes can raise doubts as to...

    Li Nan in China and North Korea (2015)

  20. No Access

    Chapter and Conference Paper

    Application Study of Spatiotemporal Chaotic Sequence in Code Division Multiple Access Communication System

    This paper presents a design plan of spatiotemporal chaos system based on the coupled map lattice model, studies the spatiotemporal chaotic sequence of balance, relevance and complexity generated by the model,...

    Li Nan, Tang Quan-bin in Advances in Computer Science and its Applications (2014)

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