101 Result(s)

Article

SETD8 inhibits apoptosis and ferroptosis of Ewing’s sarcoma through YBX1/RAC3 axis

Ewing’s sarcoma (ES) represents a rare yet exceedingly aggressive neoplasm that poses a significant health risk to the pediatric and adolescent population. The clinical outcomes for individuals with relapsed o...

Huimou Chen, **g Hu, **lin **ong, Hongling Chen, Qiaofang Liao… in Cell Death & Disease (2024)

Article

The roles of Th cells in myocardial infarction

Myocardial infarction, commonly known as a heart attack, is a serious condition caused by the abrupt stoppage of blood flow to a part of the heart, leading to tissue damage. A significant aspect of this condit...

Jun Liu, Feila Liu, Tingting Liang, Yue Zhou, **aohan Su, Xue Li… in Cell Death Discovery (2024)

Article

Hsa_circ_0021205 enhances lipolysis via regulating miR-195-5p/HSL axis and drives malignant progression of glioblastoma

Abnormal lipid metabolism is an essential hallmark of glioblastoma. Hormone sensitive lipase (HSL), an important rate-limiting enzyme contributed to lipolysis, which was involved in aberrant lipolysis of gliob...

Suwen Li, Jiaqi Yuan, Zhe Cheng, Yongdong Li, Shan Cheng… in Cell Death Discovery (2024)

Article

AURKA inhibition induces Ewing’s sarcoma apoptosis and ferroptosis through NPM1/YAP1 axis

Ewing’s sarcoma (ES) is a rare and highly aggressive malignant tumor arising from bone and soft tissue. Suffering from intractable or recurrent diseases, the patients’ therapy options are very limited. It is e...

Huimou Chen, **g Hu, **lin **ong, Hongling Chen, Biaojun Lin… in Cell Death & Disease (2024)

Article

Correction: Anti-Inflammatory Mechanism of Walnut Meal Peptide/ Ellagic Acid Nanoparticles on LPS-Stimulated RAW264.7 Cells by Inhibition of NFκB and MAPK Activation

Yuxi Ling, Yanxia Feng, Ziqi Li, Le Cheng… in International Journal of Peptide Research … (2023)

Article

Aldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect

Colorectal cancer (CRC) is a prevalent malignancy worldwide and is associated with a high mortality rate. Changes in bioenergy metabolism, such as the Warburg effect, are often observed in CRC. Aldolase B (ALD...

Yu-De Chu, Li-Chun Cheng, Siew-Na Lim, Ming-Wei Lai, Chau-Ting Yeh… in Cell Death & Disease (2023)

Article

Plasma cell-free DNA promise monitoring and tissue injury assessment of COVID-19

Coronavirus 2019 (COVID-19) is a complex disease that affects billions of people worldwide. Currently, effective etiological treatment of COVID-19 is still lacking; COVID-19 also causes damages to various orga...

**n **, Yanqun Wang, **** Xu, Yimin Li, Fanjun Cheng… in Molecular Genetics and Genomics (2023)

Article

Venlafaxine antagonizes the noradrenaline-promoted colon cancer progression by inhibiting the norepinephrine transporter

Epidemiological studies have demonstrated that the use of antidepressants is associated with a decreased risk of colorectal cancer (CRC); however, the mechanisms behind this association are yet unknown. Adrene...

Huahua Zhang, Jiming Han, **g Zhang, Jiyu Miao, Fang Li… in Cell Death Discovery (2023)

Article

GWAS of grain color and tannin content in Chinese sorghum based on whole-genome sequencing

Seventy-three QTL related to grain color and tannin content were identified in Chinese sorghum accessions, and a new recessive allelic variant of TAN2 gene was discovered.

Liyi Zhang, Jianxia Xu, Yanqing Ding, Ning Cao, Xu Gao… in Theoretical and Applied Genetics (2023)

Article

The RXFP2-PLC/PKC signaling pathway mediates INSL3-induced regulation of the proliferation, migration and apoptosis of mouse gubernacular cells

Testicular hypoplasia can affect the sexual and reproductive ability in adulthood, and even increase the risk of cancer. Abnormal development of the gubernaculum is one of the important factors of testicular h...

Shouxing Duan, Xuewu Jiang, Jianhong Li, Maxian Fu… in Cellular & Molecular Biology Letters (2023)

Article

METTL3 knockdown promotes temozolomide sensitivity of glioma stem cells via decreasing MGMT and APNG mRNA stability

Chemo-resistance hinders the therapeutic efficacy of temozolomide (TMZ) in treating glioblastoma multiforme (GBM). Recurrence of GBM even after combination of maximal tumor resection, concurrent radio-chemothe...

Jia Shi, Peng Zhang, Xuchen Dong, Jiaqi Yuan, Yongdong Li, Suwen Li… in Cell Death Discovery (2023)

Article

Use of mouse primary epidermal organoids for USA300 infection modeling and drug screening

Skin infections caused by drug-resistant Staphylococcus aureus occur at high rates nationwide. Mouse primary epidermal organoids (mPEOs) possess stratified histological and morphological characteristics of epider...

**aorui **e, Xuebo Tong, Zhihong Li, Quan Cheng, **aowei Wang… in Cell Death & Disease (2023)

Article

CircRNF144B/miR-342-3p/FBXL11 axis reduced autophagy and promoted the progression of ovarian cancer by increasing the ubiquitination of Beclin-1

Circular RNAs (circRNAs) can regulate autophagy and ovarian cancer (OC) progression. However, autophagy-associated circRNAs involved in OC progression are largely unknown. Bioinformatics, RNA sequencing, and q...

Wenting Song, Zhirui Zeng, Yilei Zhang, Haili Li, Huimin Cheng… in Cell Death & Disease (2022)