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    Article

    Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody–drug conjugate, demonstrates in vitro and in vivo antitumor activity against primary and metastatic ovarian tumors overexpressing HER2

    High-grade serous ovarian cancer (HGSOC) and ovarian clear cell carcinoma (CC), are biologically aggressive tumors endowed with the ability to rapidly metastasize to the abdominal cavity and distant organs. Ab...

    Levent Mutlu, Blair McNamara, Stefania Bellone in Clinical & Experimental Metastasis (2024)

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    Article

    Characterization of Bone Marrow Progenitor Cell Uterine Engraftment and Transdifferentiation

    Regeneration of uterine tissue is an important physiological process that allows for maintenance of fertility after menstruation or pregnancy. Stem cells, especially bone marrow–derived progenitors, play a cru...

    Ramanaiah Mamillapalli, Levent Mutlu, Hugh S. Taylor in Reproductive Sciences (2022)

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    Open Access

    Therapeutic role of uterine-derived stem cells in acute kidney injury

    Acute kidney injury (AKI) causes abrupt deterioration in kidney function that disrupts metabolic, electrolyte and fluid homeostasis. Although the prevalence of AKI is steadily increasing, no definitive treatme...

    Ramanaiah Mamillapalli, SiHyun Cho, Levent Mutlu in Stem Cell Research & Therapy (2022)