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Article
Open AccessCirculating sphingolipids and relationship to cardiac remodelling before and following a low-energy diet in asymptomatic Type 2 Diabetes
Heart failure with preserved ejection fraction (HFpEF) is a heterogenous multi-system syndrome with limited efficacious treatment options. The prevalence of Type 2 diabetes (T2D) continues to rise and predispo...
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Article
Open AccessActivity of the adrenomedullin system to personalise post-discharge diuretic treatment in acute heart failure
Quantifying the activity of the adrenomedullin system might help to monitor and guide treatment in acute heart failure (AHF) patients. The aims were to (1) identify AHF patients with marked benefit or harm fro...
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Article
Open AccessEffects of late, repetitive remote ischaemic conditioning on myocardial strain in patients with acute myocardial infarction
Late, repetitive or chronic remote ischaemic conditioning (CRIC) is a potential cardioprotective strategy against adverse remodelling following ST-segment elevation myocardial infarction (STEMI). In the random...
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Article
Open AccessLabPipe: an extensible bioinformatics toolkit to manage experimental data and metadata
Data handling in clinical bioinformatics is often inadequate. No freely available tools provide straightforward approaches for consistent, flexible metadata collection and linkage of related experimental data ...
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Article
Open AccessLarger infarct size associated with dysglycemia at the time of ST-elevation myocardial infarction is related to later presentation