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  1. Article

    Open Access

    Cardiovascular Insights for the Appropriate Management of Chronic Venous Disease: A Narrative Review of Implications for the Use of Venoactive Drugs

    Evidence suggests that chronic venous disease (CVD) may be a cardiovascular disorder, as patients with CVD are prone to develo** arterial (atherosclerosis) and venous (thromboembolism) diseases. This may be ...

    Sergio Gianesini, Leonardo De Luca, Toni Feodor, Wassila Taha in Advances in Therapy (2023)

  2. Article

    Open Access

    Screening and management of dyslipidemia in oncologic patients undergoing cardiotoxic therapies: results from an Italian survey

    Baseline cardiovascular risk factors correction is recommended in all cancer patients undergoing potentially cardiotoxic therapies. Despite available guidelines, real-world data on dyslipidemia prevalence and ...

    Massimiliano Camilli, Irma Bisceglia, Maria Laura Canale in Cardio-Oncology (2023)

  3. No Access

    Article

    One-year clinical outcome of patients with left ventricular thrombus after acute myocardial infarction discharged on triple or dual antithrombotic therapy

    In patients with left ventricular thrombus (LVT) after acute myocardial infarction (MI), both anticoagulant and antiplatelet therapies are needed. It is unknown whether dual antithrombotic therapy (DAT) is abl...

    Leonardo De Luca, Rita Lucia Putini in Journal of Thrombosis and Thrombolysis (2022)

  4. No Access

    Article

    Effectiveness of fondaparinux vs unfractionated heparin following percutaneous coronary intervention in survivors of out-of-hospital cardiac arrest due to acute myocardial infarction

    There is no specific evidence on the antithrombotic management of survivors of out-of-hospital cardiac arrest (OHCA) due to acute myocardial infarction (AMI). We sought to compare the short-term outcome of unf...

    Leonardo De Luca, Massimo Uguccioni in European Journal of Clinical Pharmacology (2021)

  5. No Access

    Article

    Established and Emerging Pharmacological Therapies for Post-Myocardial Infarction Patients with Heart Failure: a Review of the Evidence

    After an episode of myocardial infarction (MI), patients remain at risk for recurrent ischemic events, heart failure (HF), and sudden death. Post-MI patients with left ventricular systolic dysfunction (LVSD) h...

    Leonardo De Luca in Cardiovascular Drugs and Therapy (2020)

  6. Article

    Open Access

    Comparison of bioresorbable vs durable polymer drug-eluting stents in unprotected left main (from the RAIN-CARDIOGROUP VII Study)

    There are limited data regarding the impact of bioresorbable polymer drug eluting stent (BP-DES) compared to durable polymer drug eluting stent (DP-DES) in patients treated with percutaneous coronary intervent...

    Mario Iannaccone, Umberto Barbero, Michele De Benedictis in BMC Cardiovascular Disorders (2020)

  7. No Access

    Article

    Lack of implementation of guidelines recommendations for coronary revascularization in stable patients with complex disease is associated with high rates of incomplete revascularization

    The objective of this study is to evaluate completeness of coronary revascularization in patients with complex stable coronary artery disease (SCAD) who underwent percutaneous coronary interventions (PCI), but...

    Marcello Marino, Sergio Leonardi, Gabriele Crimi, Maurizio Ferrario in Heart and Vessels (2020)

  8. No Access

    Chapter

    Tumor Detection in Syndromic NET: Zollinger-Ellison Syndrome

    The Zollinger-Ellison syndrome (ZES) is a clinical disorder characterized by recurrent peptic ulcers due to hypergastrinemia induced by a gastrinoma, a gastrin-secreting neuroendocrine tumor. ZES is sporadic i...

    Roberta Modica, Luigi Camera, Vincenzo Napolitano in Neuroendocrine Tumors in Real Life (2018)

  9. No Access

    Article

    Role of 68Ga-DOTATATE PET/CT in patients with multiple endocrine neoplasia type 1 (MEN1)

    Multiple endocrine neoplasia type 1 (MEN1) is a hereditary syndrome predisposing to many endocrine and neuroendocrine tumors (NET). Conventional imaging (CI) cannot provide satisfactory results for all the dif...

    Secondo Lastoria, Francesca Marciello, Antongiulio Faggiano, Luigi Aloj in Endocrine (2016)

  10. No Access

    Article

    Prognostic role of N-terminal pro-brain natriuretic peptide in asymptomatic hypertensive and diabetic patients in primary care: impact of age and gender

    The association between natriuretic peptides and clinical outcome in asymptomatic hypertensive and diabetic patients with no clinical evidence of heart failure (HF) is still unclear. We assessed the prognostic...

    Piercarlo Ballo, Irene Betti, Alessandro Barchielli in Clinical Research in Cardiology (2016)

  11. No Access

    Article

    Everolimus-Eluting Bioresorbable Vascular Scaffold System in the Treatment of Cardiac Allograft Vasculopathy: the CART (Cardiac Allograft Reparative Therapy) Prospective Multicenter Pilot Study

    Cardiac allograft vasculopathy (CAV) is a form of accelerated atherosclerosis, which represents the leading cause of late morbidity and mortality after heart transplantation. The recent bioresorbable vascular ...

    Michele Pighi, Fabrizio Tomai in Journal of Cardiovascular Translational Re… (2016)

  12. No Access

    Reference Work Entry In depth

    Biomarkers of Coronary Plaque Composition and Vulnerability

    An important challenge to facing the epidemic of cardiovascular disease is the unpredictable nature of acute coronary events. Therefore, substantial research has been recently conducted in order to develop new...

    Leonardo De Luca, Fabrizio Tomai in Biomarkers in Cardiovascular Disease (2016)

  13. No Access

    Living Reference Work Entry In depth

    Biomarkers of Coronary Plaque Composition and Vulnerability

    An important challenge to facing the epidemic of cardiovascular disease is the unpredictable nature of acute coronary events. Therefore, substantial research has been recently conducted in order to develop new...

    Leonardo De Luca, Fabrizio Tomai in Biomarkers in Cardiovascular Disease

  14. No Access

    Chapter

    The History of Research on Coronary Stenting

    There are few technical developments that have changed the face of interventional cardiology as much and as rapidly as the practice of the placement of intracoronary stents. The first stents were implanted in ...

    Fabrizio Tomai, Leonardo De Luca in Dawn and Evolution of Cardiac Procedures (2013)

  15. No Access

    Article

    Hyponatremia in acute heart failure syndromes: A potential therapeutic target

    Mild hyponatremia is common in patients hospitalized for worsening heart failure, and it is a major predictor of post-discharge mortality and morbidity irrespective of left ventricular ejection fraction. Recen...

    Filippo Brandimarte, Francesco Fedele, Leonardo De Luca in Current Heart Failure Reports (2007)

  16. No Access

    Article

    Acute heart failure syndromes: clinical scenarios and pathophysiologic targets for therapy

    Acute heart failure syndromes (AHFS) represent the most common discharge diagnosis in patients over age 65 years, with an exceptionally high mortality and readmission rates at 60–90 days. Recent surveys and re...

    Leonardo De Luca, Gregg C. Fonarow, Kirkwood F. Adams Jr. in Heart Failure Reviews (2007)

  17. No Access

    Article

    Pharmacological treatment of chronic heart failure

    Heart failure (HF) is associated with a high morbidity and mortality in the Western World. Our knowledge of the epidemiology, pathophysiology, and therapy has improved dramatically during the last 20 years. Ph...

    Rachele Adorisio, Leonardo De Luca, Joseph Rossi in Heart Failure Reviews (2006)

  18. No Access

    Article

    Effects of levosimendan on systemic and regional hemodynamics in septic myocardial depression

    Calcium desensitization plays an important part in the pathophysiology of septic myocardial depression. We postulated that levosimendan, a new calcium sensitizer, would be beneficial in sepsis-induced cardiac ...

    Andrea Morelli, Stefano De Castro, Jean-Louis Teboul in Intensive Care Medicine (2005)

  19. No Access

    Article

    Relationship Between Hiatal Hernia and Inguinal Hernia

    Several theories explain the development of hiatal hernia (HH). Since inguinal hernia (IH) is due to abdominal wall herniation, we hypothesized that if HH is caused by an excessive “push” from increased intraa...

    Leonardo De Luca, Pietro Di Giorgio in Digestive Diseases and Sciences (2004)

  20. No Access

    Article

    Sex Determination of Bovine Embryos by Restriction Fragment Polymorphisms of PCR Amplified ZFX/ZFY Loci

    We have obtained the DNA sequence of a region from the bovine ZFY and ZFX loci and used it to design nested primers that, together with a previously described PstI polymorphism, were applied in a sensitive PCR...

    Guido D. Pollevick, Susana Giambiagi, Sabrina Mancardi, Leonardo De Luca in Bio/Technology (1992)