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2 Result(s)
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Article
Open AccessIncreased expression of upstream TH2-cytokines in a mouse model of viral-induced asthma exacerbation
Exacerbations of asthma caused by respiratory viral infections are serious conditions in need of novel treatment. To this end animal models of asthma exacerbations are warranted. We have shown that dsRNA chall...
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Article
Open AccessRhinoviral stimuli, epithelial factors and ATP signalling contribute to bronchial smooth muscle production of IL-33
Bronchial smooth muscle cells (BSMCs) from severe asthmatics have been shown to overexpress the Th2-driving and asthma-associated cytokine IL-33. However, little is known regarding factors involved in BSMC pro...
