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Article
Open AccessClinical presentation and antimicrobial resistance of invasive Escherichia coli disease in hospitalized older adults: a prospective multinational observational study
Clinical data characterizing invasive Escherichia coli disease (IED) are limited. We assessed the clinical presentation of IED and antimicrobial resistance (AMR) patterns of causative E. coli isolates in older ad...
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Article
Open AccessIncidence and predictive biomarkers of Clostridioides difficile infection in hospitalized patients receiving broad-spectrum antibiotics
Trial enrichment using gut microbiota derived biomarkers by high-risk individuals can improve the feasibility of randomized controlled trials for prevention of Clostridioides difficile infection (CDI). Here, we r...
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Article
Open AccessDistinct impact of antibiotics on the gut microbiome and resistome: a longitudinal multicenter cohort study
The selection pressure exercised by antibiotic drugs is an important consideration for the wise stewardship of antimicrobial treatment programs. Treatment decisions are currently based on crude assumptions, an...
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Article
Vancomycin-resistant enterococci (VRE): a reason to isolate?
In recent years, an increase in invasive VRE infections has been reported worldwide, including Germany. The most common gene encoding resistance to glycopeptides is VanA, but predominant VanB clones are emergi...
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Article
Fecal microbiota transplantation in a kidney transplant recipient with recurrent urinary tract infection
We report on a kidney transplant recipient treated with fecal microbiota transplantation (FMT) for recurrent urinary tract infections.
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Article
Open AccessScreening and contact precautions – A survey on infection control measures for multidrug-resistant bacteria in German university hospitals
To assess the scope of infection control measures for multidrug-resistant bacteria in high-risk settings, a survey among university hospitals was conducted. Fourteen professionals from 8 sites participated. Re...
