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  1. Article

    Open Access

    Interleukin-4 Modulates Neuroinflammation by Inducing Phenotypic Transformation of Microglia Following Subarachnoid Hemorrhage

    Neuroinflammation, a key pathological feature following subarachnoid hemorrhage (SAH), can be therapeutically targeted by inhibiting microglia M1 polarization and promoting phenotypic transformation to M2 micr...

    **g Wang, Lili Wang, Qingjian Wu, Yichen Cai, Chengfu Cui, Ming Yang… in Inflammation (2024)

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  2. Article

    Author Correction: Roflumilast Reduces Cerebral Inflammation in a Rat Model of Experimental Subarachnoid Hemorrhage

    Qingjian Wu, Lifeng Qi, Hanxia Li, Leilei Mao, Mingfeng Yang, Rongxia **e… in Inflammation (2023)

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    Article

    Carbonyl Reductase 1 Attenuates Ischemic Brain Injury by Reducing Oxidative Stress and Neuroinflammation

    Oxidative stress and neuroinflammatory response after the ischemic injury are important pathophysiologic mechanisms that cause brain tissue loss and neurological deficit. This study aims to observe the express...

    Leilei Mao, Kun Wang, Pengjie Zhang, Shihao Ren… in Translational Stroke Research (2021)

  4. No Access

    Article

    Roflumilast Reduces Cerebral Inflammation in a Rat Model of Experimental Subarachnoid Hemorrhage

    Roflumilast, a selective inhibitor for PDE4, is approved by FDA as an anti-inflammation drug for treatment of chronic obstructive pulmonary disease (COPD). This study investigates the effects of roflumilast on...

    Qingjian Wu, Lifeng Qi, Hanxia Li, Leilei Mao, Mingfeng Yang, Rongxia **e… in Inflammation (2017)

  5. No Access

    Chapter

    The Critical Roles of Immune Cells in Acute Brain Injuries

    Acute brain injuries elicit prompt and robust immune responses characterized by the activation of local glial cells and mobilization of peripheral leukocytes. The activation of immune cells originally aims to ...

    Peiying Li, Yu Gan, Leilei Mao, Rehana Leak… in Immunological Mechanisms and Therapies in … (2014)