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Article
Preparing for CAR T cell therapy: patient selection, bridging therapies and lymphodepletion
Chimeric antigen receptor (CAR) T cells have emerged as a potent therapeutic approach for patients with certain haematological cancers, with multiple CAR T cell products currently approved by the FDA for those...
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Article
Open AccessDevelopment and validation of a guideline on sexual and reproductive health services for polycystic ovary syndrome in Iran: a mixed-methods study protocol
Sexual and reproductive health (SRH) is an important aspect of women's health. Polycystic ovary syndrome is a common disease among women and has long-term negative effects on women’s health. Evidence shows tha...
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Article
Open AccessFunctional Surfactants for Molecular Fishing, Capsule Creation, and Single-Cell Gene Expression
We have demonstrated how to create a parent surfactant that is open to manipulation, while maintaining its surface activity, robustness, and compatibility,...
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Article
Open AccessThe role of soluble mediators in the clinical course of EBV infection and B cell homeostasis after kidney transplantation
Epstein-Barr virus (EBV) reactivation can lead to serious complications in kidney transplant patients, including post-transplant lymphoproliferative disorder (PTLD). Here, we have assessed the impact of EBV on...
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Article
Open AccessThe relationship between health life style and spermogram Indicators among infertile men: preliminary data
Inappropriate life style has destructive effects on sperm quality and, male fertility, so that lifestyle modification may improve spermogram indexes preliminary data. This study aimed to determine the relation...
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Article
High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population
The discovery of the highly efficient site-specific nuclease system CRISPR–Cas9 from Streptococcus pyogenes has galvanized the field of gene therapy1,2. The immunogenicity of Cas9 nuclease has been demonstrated i...
