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    Article

    Intracellular leucine-rich alpha-2-glycoprotein-1 competes with Apaf-1 for binding cytochrome c in protecting MCF-7 breast cancer cells from apoptosis

    Leucine-rich alpha-2-glycoprotein-1 (LRG1) has been shown to compete with apoptosis activating factor-1 (Apaf-1) for binding cytochrome c (Cyt c) and could play a role in inhibition of apoptosis. Employing MCF-7 ...

    Ronald Jemmerson, Katherine Staskus, LeeAnn Higgins, Kathleen Conklin… in Apoptosis (2021)

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    Article

    Novel Biomarker Candidates to Predict Hepatic Fibrosis in Hepatitis C Identified by Serum Proteomics

    Liver biopsy remains the gold standard to assess hepatic fibrosis. It is desirable to predict hepatic fibrosis without the need for invasive liver biopsy. Proteomic techniques allow unbiased assessment of prot...

    Libang Yang, Kyle D. Rudser, LeeAnn Higgins… in Digestive Diseases and Sciences (2011)