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Article
Comparison of laryngeal mask airway and endotracheal tube placement in neonates
We hypothesize that the time, number of attempts, and physiologic stability of placement of an LMA would be superior compared to ETT.
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Article
BMI metrics and their association with adiposity, cardiometabolic risk factors, and biomarkers in children and adolescents
There are limited data comparing the relative associations of various BMI metrics with adiposity and cardiometabolic risk factors in youth.
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Article
Open AccessAbnormally increased carotid intima media-thickness and elasticity in patients with Morquio A disease
Cardiovascular disease frequently causes morbidity and mortality in mucopolysaccharidoses (MPS); however, cardiovascular anatomy and dysfunction in MPS IVA (Morquio A disease) is not well described. Consequent...
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Article
Relation of secondhand smoke exposure to vascular phenotypes in children and adolescents
Subclinical cardiovascular risks of secondhand smoke (SHS) exposure among children and adolescents remains insufficiently described.
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Article
Mortality after hematopoietic stem cell transplantation for severe mucopolysaccharidosis type I: the 30-year University of Minnesota experience
Mucopolysaccharidosis IH (MPS IH, Hurler syndrome) naturally leads to death within the first decade of life, primarily from cardiac and pulmonary causes. To determine how hematopoietic stem cell transplantatio...
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Article
Angiotensin receptor blockade mediated amelioration of mucopolysaccharidosis type I cardiac and craniofacial pathology
Mucopolysaccharidosis type I (MPS IH) is a lysosomal storage disease (LSD) caused by inactivating mutations to the alpha-L-iduronidase (IDUA) gene. Treatment focuses on IDUA enzyme replacement and currently emplo...
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Chapter
Delayed Infusion Reactions to Enzyme Replacement Therapies
Background: There are currently ten intravenous enzyme replacement therapy (ERT) products available for the treatment of eight different lysosomal diseases (LD) in the USA. Additional ERT products are in...
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Article
Impaired cardiac autonomic nervous system function is associated with pediatric hypertension independent of adiposity
We examined whether sympathetic nervous system activity influences hypertension status and systolic blood pressure (SBP) independent of adiposity in youth ranging from normal-weight to severe obesity.
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Article
Novel Biomarker Candidates to Predict Hepatic Fibrosis in Hepatitis C Identified by Serum Proteomics
Liver biopsy remains the gold standard to assess hepatic fibrosis. It is desirable to predict hepatic fibrosis without the need for invasive liver biopsy. Proteomic techniques allow unbiased assessment of prot...