367 Result(s)
within
Le-** Zhang
English
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Article
A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
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ABBV-744 alleviates LPS-induced neuroinflammation via regulation of BATF2-IRF4-STAT1/3/5 axis
Suppression of neuroinflammation using small molecule compounds targeting the key pathways in microglial inflammation has attracted great interest. Recently, increasing attention has been gained to the role of...
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Article
Discovery of a selective TRF2 inhibitor FKB04 induced telomere shortening and senescence in liver cancer cells
Telomere repeat binding factor 2 (TRF2), a critical element of the shelterin complex, plays a vital role in the maintenance of genome integrity. TRF2 overexpression is found in a wide range of malignant cancer...
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Open AccessCircPIAS1 promotes hepatocellular carcinoma progression by inhibiting ferroptosis via the miR-455-3p/NUPR1/FTH1 axis
The role of circRNAs in hepatocellular carcinoma (HCC) progression remains unclear. CircPIAS1 (circBase ID: hsa_circ_0007088) was identified as overexpressed in HCC cases through bioinformatics analysis. This ...
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Open AccessEpidemiological characteristics of tuberculosis incidence and its macro-influence factors in Chinese mainland during 2014–2021
Tuberculosis (TB) remains a pressing public health issue, posing a significant threat to individuals' well-being and lives. This study delves into the TB incidence in Chinese mainland during 2014–2021, aiming ...
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Article
A New 1,6-Seco-Norisoprenoid from the Leaves and Twigs of Croton yanhuii
A new 1,6-seco-norisoprenoid, named croyanhuin G (1), together with ten known norisoprenoids (2–11), was isolated from the leaves and twigs of Croton yanhuii Y. T. Chang (Euphorbiaceae). The structure of this new...
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Proposing a machine learning approach to analyze and predict basic high-temperature properties of iron ore fines and its factors
The basic high-temperature properties of iron ore play a crucial role in optimizing sintering and ore blending, but the testing process for these properties is complex and has significant lag time, which canno...
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Jeotgalibacillus haloalkalitolerans sp. nov., a novel alkalitolerant and halotolerant bacterium, isolated from the confluence of the Fenhe River and the Yellow River
A Gram-stain positive, aerobic, alkalitolerant and halotolerant bacterium, designated HH7-29 T, was isolated from the confluence of the Fenhe River and the Yellow River in Shanxi Province, PR China. Growth occurr...
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Article
Magnetic enhancement of road dusts in Shanghai and its implications for the urban environment
Road dust samples in Baoshan District, Shanghai, were collected to explore magnetic and chemical properties of atmospheric dustfall in urban areas, intensively impacted by anthropogenic activities. Magnetic pa...
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Article
FOXP4-AS1 promotes CD8+ T cell exhaustion and esophageal cancer immune escape through USP10-stabilized PD-L1
Esophageal cancer (EC) is the 9th most frequently diagnosed malignancy globally with unfavorable prognosis. Immune escape is one of the principal factors leading to poor survival, however, the mechanism underl...
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Article
Microstructure and microtexture evolution characteristics of a powder metallurgy Ni-based superalloy during static recrystallization
Static recrystallization (SRX) characteristics of a powder metallurgy superalloy were investigated by isothermal compression at 1080–1170 °C under strain rates of 0.01–0.1 s−1, strains of 0.1, 0.22, or 0.5, and h...
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Article
Open AccessTowards an actionable One Health approach
Despite the increasing focus on strengthening One Health capacity building on global level, challenges remain in devising and implementing real-world interventions particularly in the Asia-Pacific region. Reco...
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Visible-Light-Mediated Cyclization of Arylamines with Aldehydes Using CdSe/CdS Quantum Dots and Titanium Dioxide Nanotube Composite
We report an efficient and simple method for the synthesis of core–shell quantum dots CdSe/CdS in aqueous media under normal pressure. This QDs was successfully loaded on the surface of titanium dioxide nanotu...
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Article
Re-assessment of the close relationship between serum FSH levels and semen quality: a retrospective cohort study of 11,929 Chinese men
To establish a medically valuable normal reference interval of follicle-stimulating hormone (FSH) levels in males with normal semen and to assess the predictive value of FSH in males exhibiting semen abnormali...
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Article
Geriatric nutrition risk index: a more powerful index identifying muscle mass loss in patients with rheumatoid arthritis
To explore the association of geriatric nutrition risk index (GNRI), a traditional albumin-body weight calculation, with myopenia in patients with rheumatoid arthritis (RA) and compare its ability to identify ...
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Article
Facile and effective synthesis strategy for terbium-doped hydroxyapatite toward photoelectric devices and flexible functional fibers
As a material with good biocompatibility, hydroxyapatite (HAP) can have optical properties after do** with various rare earth ions. As a biocompatible fluorescent material, doped HAP could have broad applica...
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Open AccessCorrection: Seasonality of respiratory syncytial virus infection in children hospitalized with acute lower respiratory tract infections in Hunan, China, 2013–2022
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Purinergic P2X7 receptor involves in anti-retinal photodamage effects of berberine
Berberine (BBR) is a Chinese herb with antioxidant and anti-inflammatory properties. In a previous study, we found that BBR had a protective effect against light-induced retinal degeneration in BALB/c mice. Th...
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Open AccessSeasonality of respiratory syncytial virus infection in children hospitalized with acute lower respiratory tract infections in Hunan, China, 2013–2022
In China, respiratory syncytial virus (RSV) infections traditionally occur during the spring and winter seasons. However, a shift in the seasonal trend was noted in 2020–2022, during the coronavirus disease 20...
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Article
Solibacillus ferritrahens sp. nov., a novel siderophore-producing bacterium isolated from Wumeng Mountain National Nature Reserve in Yunnan Province
A gram-stain-positive, aerobic, rod-shaped bacterial strain capable of producing siderophores, named YIM B08730T, was isolated from a soil sample collected from Wumeng Mountain National Nature Reserve, Zhaotong C...
