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  1. Article

    Open Access

    Publisher Correction: Dietary thiols accelerate aging of C. elegans

    Ivan Gusarov, Ilya Shamovsky, Bibhusita Pani, Laurent Gautier in Nature Communications (2021)

  2. Article

    Open Access

    Dietary thiols accelerate aging of C. elegans

    Glutathione (GSH) is the most abundant cellular antioxidant. As reactive oxygen species (ROS) are widely believed to promote aging and age-related diseases, and antioxidants can neutralize ROS, it follows that...

    Ivan Gusarov, Ilya Shamovsky, Bibhusita Pani, Laurent Gautier in Nature Communications (2021)

  3. No Access

    Chapter and Conference Paper

    Impact of Textual Data Augmentation on Linguistic Pattern Extraction to Improve the Idiomaticity of Extractive Summaries

    The present work aims to develop a text summarisation system for financial texts with a focus on the fluidity of the target language. Linguistic analysis shows that the process of writing summaries should take...

    Abdelghani Laifa, Laurent Gautier in Big Data Analytics and Knowledge Discovery (2021)

  4. Protocol

    Sharing Programming Resources Between Bio* Projects

    Open-source software encourages computer programmers to reuse software components written by others. In evolutionary bioinformatics, open-source software comes in a broad range of programming languages, includ...

    Raoul J. P. Bonnal, Andrew Yates, Naohisa Goto, Laurent Gautier in Evolutionary Genomics (2019)

  5. Article

    Open Access

    Mechanism of biofilm-mediated stress resistance and lifespan extension in C. elegans

    Bacteria naturally form communities of cells known as biofilms. However the physiological roles of biofilms produced by non-pathogenic microbiota remain largely unknown. To assess the impact of a biofilm on ho...

    Olga Smolentseva, Ivan Gusarov, Laurent Gautier, Ilya Shamovsky in Scientific Reports (2017)

  6. Article

    Open Access

    Glycogen controls Caenorhabditis elegans lifespan and resistance to oxidative stress

    A high-sugar diet has been associated with reduced lifespan in organisms ranging from worms to mammals. However, the mechanisms underlying the harmful effects of glucose are poorly understood. Here we establis...

    Ivan Gusarov, Bibhusita Pani, Laurent Gautier, Olga Smolentseva in Nature Communications (2017)

  7. No Access

    Article

    Transcriptional interactions suggest niche segregation among microorganisms in the human gut

    The human gastrointestinal (GI) tract is the habitat for hundreds of microbial species, of which many cannot be cultivated readily, presumably because of the dependencies between species1. Studies of microbial co...

    Damian Rafal Plichta, Agnieszka Sierakowska Juncker in Nature Microbiology (2016)

  8. No Access

    Article

    Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes

    Sequencing the microbial species present in complex metagenomic samples is made easier with a method that groups genes by co-abundance.

    H Bjørn Nielsen, Mathieu Almeida, Agnieszka Sierakowska Juncker in Nature Biotechnology (2014)

  9. Article

    Addendum: Enterotypes of the human gut microbiome

    Manimozhiyan Arumugam, Jeroen Raes, Eric Pelletier, Denis Le Paslier in Nature (2014)

  10. No Access

    Protocol

    Sharing Programming Resources Between Bio* Projects Through Remote Procedure Call and Native Call Stack Strategies

    Open-source software (OSS) encourages computer programmers to reuse software components written by others. In evolutionary bioinformatics, OSS comes in a broad range of programming languages, including C/C++, ...

    Pjotr Prins, Naohisa Goto, Andrew Yates, Laurent Gautier in Evolutionary Genomics (2012)

  11. Article

    Erratum: Enterotypes of the human gut microbiome

    Nature 473, 174–180 (2011) In this Letter, we inadvertently omitted Karsten Kristiansen, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK-2200 Copenhagen, Denmark, from the MetaHIT Consor...

    Manimozhiyan Arumugam, Jeroen Raes, Eric Pelletier, Denis Le Paslier in Nature (2011)

  12. No Access

    Article

    Enterotypes of the human gut microbiome

    Our knowledge of species and functional composition of the human gut microbiome is rapidly increasing, but it is still based on very few cohorts and little is known about variation across the world. By combini...

    Manimozhiyan Arumugam, Jeroen Raes, Eric Pelletier, Denis Le Paslier in Nature (2011)

  13. Article

    Open Access

    An intuitive Python interface for Bioconductor libraries demonstrates the utility of language translators

    Computer languages can be domain-related, and in the case of multidisciplinary projects, knowledge of several languages will be needed in order to quickly implements ideas. Moreover, each computer language has...

    Laurent Gautier in BMC Bioinformatics (2010)

  14. Article

    Relating genomic variation to drug response in childhood acute lymphoblastic leukemia by multiplexed targeted sequencing

    Agata Wesolowska, Marlene D Dalgaard, Louise Borst, Laurent Gautier in Genome Biology (2010)

  15. No Access

    Article

    Photoperiodic induction of synchronous flowering near the Equator

    In tropical rainforests, 30–65% of tree species grow at densities of less than one individual per hectare1. At these low population densities, successful cross-pollination relies on synchronous flowering. In rain...

    Rolf Borchert, Susanne S. Renner, Zoraida Calle, Diego Navarrete, Alan Tye in Nature (2005)

  16. Article

    Open Access

    Bioconductor: open software development for computational biology and bioinformatics

    The Bioconductor project is an initiative for the collaborative creation of extensible software for computational biology and bioinformatics. The goals of the project include: fostering collaborative developme...

    Robert C Gentleman, Vincent J Carey, Douglas M Bates, Ben Bolstad in Genome Biology (2004)

  17. Article

    Open Access

    Alternative map** of probes to genes for Affymetrix chips

    Short oligonucleotide arrays have several probes measuring the expression level of each target transcript. Therefore the selection of probes is a key component for the quality of measurements. However, once pr...

    Laurent Gautier, Morten Møller, Lennart Friis-Hansen, Steen Knudsen in BMC Bioinformatics (2004)

  18. No Access

    Chapter

    An R Package for Analyses of Affymetrix Oligonucleotide Arrays

    We describe an extensible, interactive environment for data analysis and exploration of Affymetrix oligonucleotide array probe-level data. The software utilities provided with the Affymetrix analysis suite sum...

    Rafael A. Irizarry, Laurent Gautier, Leslie M. Cope in The Analysis of Gene Expression Data (2003)

  19. Article

    A new non-linear normalization method for reducing variability in DNA microarray experiments

    Microarray data are subject to multiple sources of variation, of which biological sources are of interest whereas most others are only confounding. Recent work has identified systematic sources of variation th...

    Christopher Workman, Lars Juhl Jensen, Hanne Jarmer, Randy Berka in Genome Biology (2002)

  20. No Access

    Article

    A recent history of forest fragmentation in southwestern Ivory Coast

    This study provides monitoring and spatial analysis of forest fragmentation based on high-resolution remote sensing, in order to give a framework for assessing residual biodiversity in the Guiglo-Taï region. M...

    Cyrille Chatelain, Laurent Gautier, Rodolphe Spichiger in Biodiversity & Conservation (1996)