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    Article

    Multi-omic rejuvenation and lifespan extension on exposure to youthful circulation

    Heterochronic parabiosis (HPB) is known for its functional rejuvenation effects across several mouse tissues. However, its impact on biological age and long-term health is unknown. Here we performed extended (...

    Bohan Zhang, David E. Lee, Alexandre Trapp, Alexander Tyshkovskiy in Nature Aging (2023)

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    Open Access

    Meteorin-like is an injectable peptide that can enhance regeneration in aged muscle through immune-driven fibro/adipogenic progenitor signaling

    Pathologies associated with sarcopenia include decline in muscular strength, lean mass and regenerative capacity. Despite the substantial impact on quality of life, no pharmacological therapeutics are availabl...

    David E. Lee, Lauren K. McKay, Akshay Bareja, Yongwu Li in Nature Communications (2022)