-
Article
Open AccessAssociation between BMI, vitamin D, and estrogen levels in postmenopausal women using adjuvant letrozole: a prospective study
Studies have suggested that women with elevated BMI or 25-OH vitamin D levels may derive less benefit from AIs versus tamoxifen. We prospectively investigated whether high BMI or 25-OH vitamin D levels were as...
-
Article
Open AccessComparative analysis of copy number variations in ulcerative colitis associated and sporadic colorectal neoplasia
The incidence of and mortality from colorectal cancers (CRC) can be reduced by early detection. Currently there is a lack of established markers to detect early neoplastic changes. We aimed to identify the cop...
-
Article
Inflammatory Myofibroblastic Tumor: A Rapidly Growing Soft Tissue Mass in the Posterior Mandible
The term inflammatory myofibroblastic tumor (IMT) encompasses a diverse group of spindle cell entities that traverses a clinical and histologic spectrum, extending from reactive to benign neoplastic to highly ...
-
Article
Acute kidney injury in scrub typhus
We studied the urinary abnormalities and acute kidney injury (AKI) as per RIFLE criteria in scrub typhus.
-
Article
An intraarticular fibroma of the tendon sheath in the knee joint
Fibromas that usually occur in the tendon sheaths of the wrist and hand are extremely rare in intra-articular locations. Only five such cases in the knee joint have been reported so far. This is a case report ...
-
Article
CAG repeat length polymorphism in the androgen receptor gene and breast cancer risk: data on Indian women and survey from the world
We analyzed the length of the CAG repeats of the androgen receptor gene in Indian women with breast cancer, and compared the data with that of other populations across the world in an attempt to find a potenti...
-
Article
Open AccessCarney Complex: case report and review
Carney complex is a very rare multiple neoplasia syndrome with cardiac, cutaneous, and neural tumours with a variety of pigmented lesion of skin. We are reporting a rare case of carney complex in which left at...
-
Article
Open AccessDifferential gene expression and clonal selection during cellular transformation induced by adhesion deprivation
Anchorage independent growth is an important hallmark of oncogenic transformation. Previous studies have shown that when adhesion dependent fibroblasts were prevented from adhering to a substrate they underwen...
-
Article
Metaplastic carcinoma breast (carcinosarcoma variant)
-
Article
Pleomorphic hyalinizing angiectatic tumor of soft parts involving the upper limb
Pleomorphic hyalinizing angiectatic tumor (PHAT) of soft parts is a low grade, rare, soft tissue tumor which commonly occurs on the lower extremities of adults of either sex, though lesions in other anatomic l...
-
Article
Recurrent early pregnancy loss and endothelial nitric oxide synthase gene polymorphisms
Objective(s): Studies on the relation between endothelial nitric oxide synthase (eNOS) activity in implantation and maintenance of pregnancy highlights the importance of eNOS gene polymor...
-
Article
Chromosome inversions and a novel chromosome insertion associated with recurrent miscarriages in South India
The aim of the present study was to investigate the contribution of chromosomal abnormalities and the frequency of a particular type of aberration in couples of South Indian origin with recurrent miscarriages....
-
Article
The E1B 19K protein associates with lamins in vivo and its proper localization is required for inhibition of apoptosis
Expression of the E1B 19K protein is required to inhibit apoptosis induced by E1A during adenovirus infection and transformation. E1B 19K is homologous to Bcl-2 in function and the two proteins also share limi...
-
Chapter
Regulation of Apoptosis by the Transforming Gene Products of Adenovirus
The DNA tumor virus adenovirus infects human cells, recruits them into a proliferative state, and borrows elements of the host cell transcription, translation, and DNA replication machinery to reproduce viral ...
