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Open AccessHigh-throughput telomere length measurement at nucleotide resolution using the PacBio high fidelity sequencing platform
Telomeres are specialized nucleoprotein structures at the ends of linear chromosomes. The progressive shortening of steady-state telomere length in normal human somatic cells is a promising biomarker for age-a...
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Open AccessHoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis
The repression of telomerase activity during cellular differentiation promotes replicative aging and functions as a physiological barrier for tumorigenesis in long-lived mammals, including humans. However, the...
