7 Result(s)

Article

The relation of proinsulin and insulin to insulin sensitivity and acute insulin response in subjects with newly diagnosed Type II diabetes: the Insulin Resistance Atherosclerosis Study

Aims/hypothesis. Proinsulin concentrations are increased relative to insulin concentrations in subjects with Type II (non-insulin-dependent) diabetes mellitus. This could be secondary to hypergly...

L. Mykkänen, D. J. Zaccaro, C. N. Hales, A. Festa, S. M. Haffner in Diabetologia (1999)

Article

35th Annual Meeting of the European Association for the Study of Diabetes

A. Melander, J. Olsson, G. Lindberg, A. Salzman, T. Howard, P. Stang… in Diabetologia (1999)

Article

New variants in the glycogen synthase gene (Gln71His, Met416Val) in patients with NIDDM from eastern Finland

Impaired glycogen synthesis after insulin stimulation accounts for most of the insulin resistance in patients with non-insulin-dependent diabetes mellitus (NIDDM). The glycogen synthase gene (GYS1), which enco...

J. Rissanen, J. Pihlajamäki, S. Heikkinen, P. Kekäläinen, L. Mykkänen… in Diabetologia (1997)

Article

Total immunoreactive proinsulin, immunoreactive insulin and specific insulin in relation to conversion to NIDDM: the Mexico City Diabetes Study

Although insulin resistance and decreased insulin secretion are characteristic of established non-insulin-dependent diabetes mellitus (NIDDM), which of these metabolic abnormalities is the primary determinant...

S. M. Haffner, C. Gonzalez, L. Mykkänen, M. Stern in Diabetologia (1997)

Article

A preponderance of small dense LDL is associated with specific insulin, proinsulin and the components of the insulin resistance syndrome in non-diabetic subjects

Recently, the presence of small dense low density lipoprotein (LDL) has been postulated to be a stronger risk factor for coronary heart disease than large LDL. While small dense LDL has been associated with in...

Dr. S. M. Haffner, L. MykkÄnen, D. Robbins, R. Valdez, H. Miettinen… in Diabetologia (1995)

Article

Cardiovascular disease risk factors as predictors of Type 2 (non-insulin-dependent) diabetes mellitus in elderly subjects

Risk factors measured in a cross-sectional study in subjects aged 65–74 years living in eastern Finland were correlated with the risk of develo** diabetes 3.5 years later. Sixty-nine of 892 initially non-dia...

L. Mykkänen, J. Kuusisto, K. Pyörälä, M. Laakso in Diabetologia (1993)

Article

Prevalence of diabetes mellitus in elderly subjects in east Finland

Dr. Markku Laakso, L. Mykkänen, K. Pyörälä in Diabetologia (1987)