14 Result(s)

Article

Prognostic Significance of Tumor-Associated Inflammation in Renal Cell Carcinoma

This study analyzed tumor-associated inflammation by assessing the expression of cyclophilin A (CypA) and TNF in samples of kidney tumors of various histological types. It was shown that different histological...

O. V. Kovaleva, P. A. Podlesnaya… in Bulletin of Experimental Biology and Medic… (2024)

Article

Decrease in pool of T lymphocytes with surface phenotypes of effector and central memory cells under Influence of TCR transgenic β-chain expression

Peripheral T lymphocytes can be subdivided into naive and antigen-experienced T cells. The latter, in turn, are represented by effector and central memory cells that are identified by different profiles of act...

Yu. Yu. Silaeva, A. A. Kalinina, M. S. Vagida, L. M. Khromykh… in Biochemistry (Moscow) (2013)

Article

Recombinant human alpha-fetoprotein as a regulator of adipose tissue stromal cell activity

Recombinant human alpha-fetoprotein (rhAFP), expressed in the yeast system as a glycoprotein, has been isolated and purified to 98% by the multistep method. The testing of rhAFP in the culture of adipose tissu...

E. S. Zubkova, L. N. Semenkova, I. V. Dudich… in Russian Journal of Bioorganic Chemistry (2012)

Article

The functional role of spleen neutrophil-like cells in the immune response to allogeneic tumor cells

E. V. Maryukhnich, E. S. Zvezdova, T. V. Anfalova… in Doklady Biological Sciences (2007)

Article

Suppression of tumor cell growth by allospecific cytotoxic T-lymphocytes in vitro

T. V. Anfalova, L. M. Khromykh, D. B. Kazanskii in Doklady Biological Sciences (2007)

Article

Accumulation of Neutrophils in the Spleen of Mice Immunized with Cells of Allogenic Tumors

L. A. Pobezinskii, E. L. Pobezinskaya, E. S. Zvezdova… in Doklady Biological Sciences (2005)

Article

Cross Reactivity of T Cell Receptor on Memory CD8⁺ Cells Isolated after Immunization with Allogeneic Tumor Cells

Experiments on mice deficient in expression of class I major histocompatibility complex molecules showed that memory CD8⁺ cells recognizing the alloantigen by the direct allogeneic recognition mechanism selective...

E. L. Pobezinskaya, L. A. Pobezinskii… in Bulletin of Experimental Biology and Medic… (2004)

Article

Colorimetric In Vitro Evaluation of T-Cell Cytotoxicity

We propose a new colorimetric method for evaluation of specific T lymphocyte cytotoxicity based on the capacity of viable cells to incorporate alamar blue dye, an indicator of cell metabolic activity. This met...

L. M. Khromykh, T. V. Anfalova… in Bulletin of Experimental Biology and Medic… (2003)

Article

Polyfunctionality of Allospecific Cytotoxic T-Lymphocytes in in vitro Systems

The data presented demonstrate the capacity of allospecific cytotoxic lymphocytes to fulfill noncytolytic regulatory functions. Cytotoxic lymphocytes suppress cell proliferation induced during development of a...

T. V. Anfalova, L. M. Khromykh, D. B. Kazanskii in Russian Journal of Developmental Biology (2003)

Article

The Suppressor Activity of Allospecific Cytotoxic T lymphocytes in In Vitro Systems

T. V. Anfalova, L. M. Khromykh, D. B. Kazanskii in Doklady Biological Sciences (2003)

Article

Characteristics of the Cells-Producents of Thymic Chemotactic Factor for Bone Marrow Stem Elements

It was shown using complement-dependent cytolysis and monoclonal antibodies against CD4, CD8, and NK1.1 antigens that the cortisone-resistant CD3⁺4^–8^–NK1.1^–-thymocytes spontaneously secreted a chemotactic transmi...

T. V. Anfalova, L. M. Khromykh… in Russian Journal of Developmental Biology (2002)

Article

α-Fetoprotein-Induced Apoptosis of Cancer Cells

E. I. Dudich, L. N. Semenkova, I. V. Dudich… in Bulletin of Experimental Biology and Medic… (2000)

Article

α-Fetoprotein-induced apoptosis of cancer cells

E. I. Dudich, L. N. Semenkova, I. V. Dudich… in Bulletin of Experimental Biology and Medic… (2000)