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Article
In Vitro Effect of Flow Velocity on Aerodynamic Parameters of a Cromospir Metered Dose Inhaler
The effect of changing flow velocity on the aerodynamic particle size distribution of Cromospir metered dose inhaler (MDI) was studied using an Andersen cascade impactor (ACI) in the standard configuration des...
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Article
Kinetics of hydrolysis of five-membered C-nitroheterocycles: pyrazole, imidazole, 1,2,4-triazole, and isoxazole derivatives
Alkaline hydrolysis of mono-and dinitro derivatives of five-membered heterocycles, viz., pyrazole, imidazole, 1,2,4-triazole, and isoxazole, is accompanied by the elimination of the nitro group in the form of a n...
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Article
Hydrolytic and Reductive Transformations of Nifuroxazide
The elimination of nitro groups in the form of nitrite anions in the course of reduction and alkaline hydrolysis of the antitumor drug nifuroxazide has been studied using polarographic and photometric techniqu...
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Article
Alkaline Hydrolysis Kinetics and No-Donor Activity of Tenonitrozole
The kinetics of alkaline hydrolysis of N-(5-nitro-2-thiazolyl)-2-thiophenylcarboxamide (tenonitrozole or atrican) has been studied by photometric and polarographic techniques, and the thermodynamic parameters in ...
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Article
Sydnonimines as exogenous NO donors
Chemical oxidation of a series of sydnonimine derivatives followed by NO release was studied. Substances having alkylamine substituents in the position 3 were shown to be considerably more potent NO donors in ...
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Article
Investigation of the No-Donor Activity of the Antimicrobial Drug Tinidazole