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    Article

    Permanent diffuse alopecia after haematopoietic stem cell transplantation in childhood

    Permanent alopecia after haematopoietic stem cell transplantation (HSCT) is distressing and few studies have investigated this late effect. The aim of the study was to assess the percentage of patients with al...

    D Bresters, D C M Wanders, M Louwerens, L M Ball, M Fiocco in Bone Marrow Transplantation (2017)

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    Article

    Development of clinical practice guidelines for supportive care in childhood cancer—prioritization of topics using a Delphi approach

    Currently, very few guidelines for supportive care for children with cancer exist. In the Netherlands, nationwide guidelines are over 10 years old and mostly based on expert opinion. Consequently, there is gro...

    E. A. H. Loeffen, R. L. Mulder, L. C. M. Kremer in Supportive Care in Cancer (2015)

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    Article

    Immediate and long-term somatic effects, and health-related quality of life of BM donation during early childhood. A single-center report in 210 pediatric donors

    Since 1968, when Leiden undertook the first successful European pediatric BM transplantation with a 7-year-old sibling donor, more than 300 young children have donated BM in our unit. We first retrospectively ...

    S M van Walraven, L M Straathof, G E Switzer, A Lankester in Bone Marrow Transplantation (2013)

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    Article

    Co-infusion of ex vivo-expanded, parental MSCs prevents life-threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation

    When compared with BMT, umbilical cord blood transplantation (UCBT) is associated with a lower rate of engraftment and delayed hematological/immunological recovery. This leads to increased risk of TRM in the e...

    M E Bernardo, L M Ball, A M Cometa, H Roelofs, M Zecca in Bone Marrow Transplantation (2011)

  5. No Access

    Article

    High burden of late effects after haematopoietic stem cell transplantation in childhood: a single-centre study

    The aim of our study was to assess the cumulative incidence and severity (‘burden’) of late effects in a single-centre cohort of childhood haematopoietic stem cell transplantation (HSCT) survivors, at least 2 ...

    D Bresters, I C M van Gils, W J W Kollen, L M Ball in Bone Marrow Transplantation (2010)

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    Article

    Secundaire hemofagocytaire lymfohistiocytose bij kinderen met een hematologische maligniteit

    Hemofagocytaire lymfohistiocytose (HLH) is een zeldzaam ziektebeeld dat onder andere kan ontstaan bij kinderen die zijn gediagnosticeerd met een maligniteit. In dit artikel worden drie casus besproken van pati...

    L. F. A. Visser, K. C. J. M. Kraal, D. Bresters in Tijdschrift voor Kindergeneeskunde (2009)

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    Article

    Potential role of mesenchymal stromal cells in pediatric hematopoietic SCT

    Mesenchymal stromal cells (MSCs) can be isolated from several human tissues and expanded for clinical use. MSCs are identified by phenotypic and functional characteristics, and are poor Ag-presenting cells not...

    L M Ball, M E Bernardo, F Locatelli, R M Egeler in Bone Marrow Transplantation (2008)

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    Article

    Acute GvHD: pathogenesis and classification

    Allogeneic hematopoietic SCT (HSCT) is an established treatment for some children with life-threatening hematological disease, immune deficiencies and inborn errors of metabolism. Despite advances in preventio...

    L M Ball, R M Egeler in Bone Marrow Transplantation (2008)

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    Article

    Response to the letter by M Koyama et al

    E T Korthof, P P Snijder, A A de Graaff, A C Lankester in Bone Marrow Transplantation (2005)

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    Article

    Allogeneic bone marrow transplantation for juvenile myelomonocytic leukemia: a single center experience of 23 patients

    Juvenile myelomonocytic leukemia (JMML) is a childhood leukemia for which allogeneic BMT is the only curative therapy. At our pediatric stem cell transplantation unit, we performed 26 BMTs in 23 children (age ...

    E T Korthof, P P Snijder, A A de Graaff, A C Lankester in Bone Marrow Transplantation (2005)

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    Article

    Graft dysfunction and delayed immune reconstitution following haploidentical peripheral blood hematopoietic stem cell transplantation

    For many children with life-threatening hematological diseases, hematopoietic stem cell transplantation (HSCT) is the only curative option. In children lacking a matched related or unrelated donor and with the...

    L M Ball, A C Lankester, R G M Bredius, W E Fibbe in Bone Marrow Transplantation (2005)

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    Article

    Intravenous busulfan in children prior to stem cell transplantation: study of pharmacokinetics in association with early clinical outcome and toxicity

    We studied the pharmacokinetics of intravenous busulfan (Bu) in children in order to further optimize intravenous Bu dosing in relation to toxicity and survival. A total of 31 children undergoing Bu-based cond...

    J Zwaveling, R G M Bredius, S C L M Cremers, L M Ball in Bone Marrow Transplantation (2005)

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    Article

    Paediatric allogeneic bone marrow transplantation for homozygous β-thalassaemia, the Dutch experience

    We reviewed the results of the Dutch paediatric bone marrow transplant (BMT) program for children receiving HLA-identical BMT for β-thalassaemia major over an 18-year period. In all, 19 patients underwent a total...

    L M Ball, A C Lankester, P C Giordano, M H van Weel in Bone Marrow Transplantation (2003)

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    Chapter

    S9-Dependent Activation of 1-Nitropyrene and 3-Nitrofluoranthene in Bacterial Mutagenicity Assays

    Nitro-substituted polycyclic aromatic hydrocarbons (NO2PAH) such as 1-nitropyrene (NP) and 3-nitrofluoranthene (NFA; see Fig. 1) have been detected in diesel and other combustion emissions (Nishioka et al., 1982;...

    L. M. Ball, K. Williams, M. J. Kohan, J. Lewtas in Biological Reactive Intermediates III (1986)