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Open AccessProteomic profiling of extracellular vesicles derived from human serum for the discovery of biomarkers in Avascular necrosis
Avascular necrosis (AVN) is a medical condition characterized by the destruction of bone tissue due to a diminished blood supply. When the rate of tissue destruction surpasses the rate of regeneration, effecti...
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Article
Extracellular Vesicles from Human Adipose Tissue-Derived Mesenchymal Stem Cells Suppress RANKL-Induced Osteoclast Differentiation via miR122-5p
Researchers are increasingly interested in cell therapy using mesenchymal stem cells (MSCs) as an alternative remedy for osteoporosis, with fewer side effects. Thus, we isolated and characterized extracellular...
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Article
Open AccessA comparative study of the phenotype with kainic acid-induced seizure in DBA/2 mice from three different sources
The kainic acid-induced seizure mouse model is widely used in epilepsy research. In this study, we applied kainic acid to the subcutaneous injections of three different sources of DBA/2 mice to compare and eva...
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Article
Open AccessComparison study of the response with botulinum toxin muscle injection in the ICR mice from three different sources
Botulinum-toxin A (BoNT/A) is a widely used not only for cosmetics but also for various experimental purposes including muscle-related research. In this study, we applied BoNT/A to mouse muscle of three differ...
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Article
ENA-A actimineral resource A extends lifespan associated with antioxidant mechanism in SMP30 knockout mice
ENA-actimineral resource A (ENA-A) is an alkaline mineral water and has a few biological activities such as antioxidant activity. The aim of this study was to examine the effects of ENA-A on lifespan in mice ...