-
Article
Open AccessDifferences of respiratory mechanics in mechanical ventilation of acute respiratory distress syndrome between patients with COVID-19 and Influenza A
Whether COVID-19-induced acute respiratory distress syndrome (ARDS) should be approached differently in terms of mechanical ventilation therapy compared to other virus-induced ARDS is debatable. Therefore, we ...
-
Article
An Experimental Study on the Verification of Structural and Seismic Performance of Steel Composite Walls
In the context of steel composite wall (SC wall) standards, this study explores the relaxed provisions outlined in AISC N690 (2018), particularly concerning commonly used materials in general building construc...
-
Article
Open AccessImpact of age on mortality and transfer to long-term care in patients in an intensive care unit
In the global trend of population aging, age is one of the significant factors to be considered in critically ill patients. However, the impact of age on clinical outcomes and long-term prognosis in this popul...
-
Article
Open AccessThree-dimensional label-free morphology of CD8 + T cells as a sepsis biomarker
Sepsis is a dysregulated immune response to infection that leads to organ dysfunction and is associated with a high incidence and mortality rate. The lack of reliable biomarkers for diagnosing and prognosis of...
-
Article
An Experimental Study on Shear Performance of Reinforced Steel Fiber Recycled Aggregate Concrete Filled Square Steel Tube Column of 50 MPa
Due to the unstable strength characteristics, the use of recycled aggregates is used only for non-structural members. To use recycled aggregates for structure members, shear performance evaluation experiments ...
-
Article
Open AccessLong-term clinical course and progression of lymphangioleiomyomatosis in a single lung transplant referral centre in Korea
We aimed to describe the clinical features of lymphangioleiomyomatosis (LAM) in Korean patients and identify factors associated with progressive disease (PD). Clinical features of 54 patients with definite or ...
-
Article
Open AccessNADPH oxidase 4 signaling in a ventilator-induced lung injury mouse model
For patients with acute respiratory distress syndrome, a ventilator is essential to supply oxygen to tissues, but it may also cause lung damage. In this study, we investigated the role of NOX4 using NOX4 knock...
-
Article
Open AccessThoracic skeletal muscle quantification using computed tomography and prognosis of elderly ICU patients
In elderly ICU patients, the prevalence of skeletal muscle loss is high. Longitudinal effect of thoracic muscles, especially in elderly ICU patients, are unclear although skeletal muscle loss is related with t...
-
Article
Open AccessCorticosteroid responsiveness in patients with acute exacerbation of interstitial lung disease admitted to the emergency department
Interstitial lung disease (ILD), particularly idiopathic pulmonary fibrosis (IPF), has a poor prognosis. Corticosteroids are widely used in the treatment of acute exacerbation of ILD (AE-ILD). This study aimed...
-
Article
Open AccessEfficacy of low dose pirfenidone in idiopathic pulmonary fibrosis: real world experience from a tertiary university hospital
Pirfenidone is an antifibrotic agent that has been proven to slow down the progression of idiopathic pulmonary fibrosis (IPF). The aim of this study was to evaluate the efficacy of low-dose pirfenidone (that i...
-
Article
Open AccessDiagnosis and mortality prediction of sepsis via lysophosphatidylcholine 16:0 measured by MALDI-TOF MS
Sepsis remains a critical problem with high mortality worldwide, but there is still a lack of reliable biomarkers. We aimed to evaluate the serum lysophosphatidylcholine (LPC) 16:0 as a biomarker of sepsis usi...
-
Article
Open AccessOptimal timing of initiating continuous renal replacement therapy in septic shock patients with acute kidney injury
Acute kidney injury (AKI) in patients with septic shock is associated with high mortality, but the appropriate timing for initiating continuous renal replacement therapy (CRRT) is controversial. We retrospecti...
-
Article
Open AccessPrognostic impact of the ratio of the main pulmonary artery to that of the aorta on chest computed tomography in patients with idiopathic pulmonary fibrosis
In many clinical disorders, there is a relationship between the ratio of the diameter of the main pulmonary artery (mPA) to that of the aorta (Ao) on chest computed tomography (CT). The aim of this study was t...
-
Article
Open AccessRisk factors and clinical characteristics of Pneumocystis jirovecii pneumonia in lung cancer
Solid malignancies are associated with the development of Pneumocystis jirovecii pneumonia (PJP). This study aimed to evaluate the risk factors for PJP among patients with lung cancer. This retrospective case-con...
-
Article
Open AccessChanges in cytokine responses to TB antigens ESAT-6, CFP-10 and TB 7.7 and inflammatory markers in peripheral blood during therapy
Multiple cytokines and inflammatory markers control TB infection. We aimed to investigate the changes in multiple cytokines and inflammatory markers in active TB patients following anti-TB drug therapy. Twenty...
-
Article
Open AccessClinical implications of the plasma EphA2 receptor level in critically ill patients with septic shock
The Eph/ephrin receptor ligand system is known to play a role in inflammation induced by infection, injury, and inflammatory diseases. The present study aimed to evaluate plasma EphA2 receptor levels in critic...
-
Article
Thermal and mechanical properties of structural steel SN400 at elevated temperatures
The accurate estimation of thermal and mechanical properties is a prerequisite for the reliable fire-resistant design of steel structures, considering that steel is used as one of the main materials for buildi...
-
Article
Factors associated with the quality of life of Korean COPD patients as measured by the EQ-5D
This study evaluated the health-related quality of life measured using the EuroQol five-dimension questionnaire (EQ-5D) and the degree of airway obstruction in a Korean population using Korea National Health ...
-
Article
Prediction of short- and long-term survival for advanced cancer patients after ICU admission
Intensive care unit (ICU) admission of advanced cancer patients is controversial because it is associated with poor short-term prognosis. However, ICU admission of these patients might also result in administr...
-
Article
Factors associated with quality of life measured by EQ-5D in patients with nontuberculous mycobacterial pulmonary disease
The impact of pulmonary nontuberculous mycobacterial (pNTM) disease on health-related quality of life (HRQoL) has not received significant attention in the literature. In this study, we compared the HRQoL in p...
