-
Article
Open AccessViral remodeling of the 4D nucleome
The dynamic spatial organization of genomes across time, referred to as the four-dimensional nucleome (4DN), is a key component of gene regulation and biological fate. Viral infections can lead to a reconfigur...
-
Article
Open AccessDeep convolutional neural network-based skeletal classification of cephalometric image compared with automated-tracing software
This study aimed to investigate deep convolutional neural network- (DCNN-) based artificial intelligence (AI) model using cephalometric images for the classification of sagittal skeletal relationships and comp...
-
Article
Open AccessEpigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus
Epstein-Barr virus (EBV) genomes persist in latently infected cells as extrachromosomal episomes that attach to host chromosomes through the tethering functions of EBNA1, a viral encoded sequence-specific DNA ...
-
Article
Open AccessInvolvement of condensin in cellular senescence through gene regulation and compartmental reorganization
Senescence is induced by various stimuli such as oncogene expression and telomere shortening, referred to as oncogene-induced senescence (OIS) and replicative senescence (RS), respectively, and accompanied by ...