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  1. Article

    Open Access

    MUC16 as a serum-based prognostic indicator of prometastatic gastric cancer

    Metastatic gastric cancer (GC) presents significant clinical challenges due to its poor prognosis and limited treatment options. To address this, we conducted a targeted protein biomarker discovery study to id...

    Jieun Lee, Sang Wook Lee, So Hyun Kang, Donghyeok Seol, Mira Yoo in Scientific Reports (2024)

  2. Article

    Open Access

    Childhood adversity and suicidal ideation in older Korean adults: unraveling the mediating mechanisms of mental health, physical health, and social relationships

    Suicide rates in older adults are much higher than those in younger age groups. Given the rapid increase in the proportion of older adults in Korea and the high suicide rate of this age group, it is worth inve...

    **-kyung Lee, **hee Lee, Moo-Kwon Chung, Taeksoo Shin, Ji Young Park in BMC Psychiatry (2024)

  3. No Access

    Article

    The weldability in dissimilar joints of AA5052 and SPFC780DP steel by hybrid friction stir welding

    The dissimilar welding of aluminum alloy and steel has become increasingly attractive in the automotive industry for achieve lightweight components. However, welding of these dissimilar materials is difficult ...

    Hee-Seon Bang, Dong-Min Park, Bum-Su Go, Kyoung-Hak Kim in Welding in the World (2024)

  4. No Access

    Article

    Identification of maximal tumor size associated with negligible lymph node metastasis for endoscopic submucosal dissection of undifferentiated-type early gastric cancer

    When treating undifferentiated-type early gastric cancer (UD-EGC) that is limited to the mucosa (clinically T1a), endoscopic submucosal dissection (ESD) can be considered if the tumor is 2 cm or less and is no...

    Sung Eun Oh, Soomin Ahn, Kyoung-Mee Kim, Min-Gew Choi, Jun Ho Lee in Gastric Cancer (2024)

  5. No Access

    Article

    Pharmacokinetics and extensive intestinal first-pass effects of apigenin and its active metabolite, apigenin-7-O-glucuronide, in rats

    This study investigated the metabolism and pharmacokinetics of apigenin and its metabolite, apigenin-7-O-glucuronide (A7G), using a newly developed UPLC-MS/MS method.

    Seong-Wook Seo, Soon Ho Choi, Jung-Ki Hong in Journal of Pharmaceutical Investigation (2024)

  6. Article

    Open Access

    Limited impact of bacterial virulence on early mortality risk factors in Acinetobacter baumannii bacteremia observed in a Galleria mellonella model

    Acinetobacter baumannii (AB) has emerged as a major pathogen in vulnerable and severely ill patients. It remains unclear whether early mortality (EM) due to AB bacteremia is because of worse clinical characterist...

    Sin Young Ham, June Young Chun, Kyoung-Ho Song, Chang Kyung Kang in Scientific Reports (2024)

  7. No Access

    Article

    Anesthetic management of a patient with spinal and bulbar muscular atrophy (Kennedy’s disease)

    Jiwon Han, Yong Hun Jung, Min Kyoung Kim, Seihee Min in Die Anaesthesiologie (2024)

  8. Article

    Open Access

    2023 Korean Society of Echocardiography position paper for the diagnosis and management of valvular heart disease, part II: mitral and tricuspid valve disease

    This manuscript represents the official position of the Korean Society of Echocardiography on valvular heart diseases. This position paper focuses on the diagnosis and management of valvular heart diseases wit...

    Chi Young Shim, Eun Kyoung Kim, Dong-Hyuk Cho in Journal of Cardiovascular Imaging (2024)

  9. No Access

    Article

    Non-Mitochondrial Aconitase-2 Mediates the Transcription of Nuclear-Encoded Electron Transport Chain Genes in Fission Yeast

    Aconitase-2 (Aco2) is present in the mitochondria, cytosol, and nucleus of fission yeast. To explore its function beyond the well-known role in the mitochondrial tricarboxylic acid (TCA) cycle, we conducted ge...

    Ho-Jung Kim, Soo-Yeon Cho, Soo-** Jung, Yong-Jun Cho in Journal of Microbiology (2024)

  10. Article

    Open Access

    Differential impacts of clinical, anatomical, and procedural factors on early and late mortality following open thoracoabdominal aortic repair: a retrospective observational study

    The operative outcomes of thoracoabdominal aortic aneurysms (TAAAs) are challenged by high operative mortality and disabling complications. This study aimed to explore the baseline clinical, anatomical, and pr...

    ** Kyoung Kim, Gwan Sic Kim, Woo Seok Kim, Ho ** Kim in Journal of Cardiothoracic Surgery (2024)

  11. No Access

    Article

    Correlation of LLT-1 and NLRC4 inflammasome and its effect on glioblastoma prognosis

    LLT-1 is a well-known ligand for the natural killer (NK) cell inhibitory receptor NKRP1A. Here, we examined NLRC4 inflammasome components and LLT-1 expression in glioblastoma (GBM) tissues to elucidate potenti...

    JeongMan Park, Yu ** Kim, Minwook Lee, Dongkil Kim in Journal of Neuro-Oncology (2024)

  12. Article

    Open Access

    Desensitizing efficacy of a universal dentin adhesive containing mesoporous bioactive glass on dentin hypersensitivity: a randomized clinical trial with a split-mouth model

    This split-mouth blinded randomized controlled study compared the efficacy of a desensitizing agent with oxalate/resin polymer and a universal adhesive containing mesoporous bioactive glass (MBG) for dentin hy...

    Hyun-Jung Kim, Soram Oh, Jiyoung Kwon, Kyoung-Kyu Choi, Ji-Hyun Jang in Scientific Reports (2024)

  13. Article

    Open Access

    Red2Flpe-SCON: a versatile, multicolor strategy for generating mosaic conditional knockout mice

    Image-based lineage tracing enables tissue turnover kinetics and lineage potentials of different adult cell populations to be investigated. Previously, we reported a genetic mouse model system, Red2Onco, which ec...

    Szu-Hsien Sam Wu, Somi Kim, Heetak Lee, Ji-Hyun Lee, So-Yeon Park in Nature Communications (2024)

  14. Article

    Open Access

    Evaluation of bovine coronavirus in Korean native calves challenged through different inoculation routes

    Bovine coronavirus (BCoV) is a pneumoenteric virus that can infect the digestive and respiratory tracts of cattle, resulting in economic losses. Despite its significance, information regarding BCoV pathogenesi...

    Hyung-Chul Cho, Youngjun Kim, Yong-Il Cho, **ho Park in Veterinary Research (2024)

  15. Article

    Open Access

    Comparing two mucin secretagogues for the treatment of dry eye disease: a prospective randomized crossover trial

    This study aimed to compare the clinical efficacy and investigate patients’ preferences for two mucin secretagogues in the treatment of dry eye disease (DED). Thirty patients with DED were randomly treated wit...

    Yeonwoo **, Kyoung Yul Seo, Sun Woong Kim in Scientific Reports (2024)

  16. No Access

    Article

    Human adipose-derived stem cells genetically programmed to induce necroptosis for cancer immunotherapy

    Herein, we present human adipose-derived stem cells (ADSCs) inserted with the receptor-interacting protein kinase-3 (RIP3) gene (RP@ADSCs), which induces cell necroptosis, for tumor immunotherapy. Necroptosis ...

    Soyeon Bak, Kyoung Sub Kim, Kun Na in Cancer Gene Therapy (2024)

  17. Article

    Open Access

    SUnSeT: spectral unmixing of hyperspectral images for phenoty** soybean seed traits

    Hyperspectral features enable accurate classification of soybean seeds using linear discriminant analysis and GWAS for novel seed trait genes.

    Seok Won Jeong, Jae Il Lyu, HwangWeon Jeong, Jeongho Baek in Plant Cell Reports (2024)

  18. No Access

    Article

    Association of Cough Severity with Asthma Control and Quality of Life in Patients with Severe Asthma

    Symptoms are important components in determining asthma control and in the adjustment of treatment levels. However, clinical relevance of cough in severe asthma is not well-understood. This study aimed to eval...

    Hwa Young Lee, Youngsoo Lee, Ji-Hyang Lee, Seung-Eun Lee, Da Woon Sim, Noeul Kang in Lung (2024)

  19. No Access

    Article

    HVPE growth of Si crystal with topological chiral morphology

    Topological chiral occurs when a crystal has an asymmetric structure that does not overlap with the mirror image. In this study, Si crystals with a topological chiral morphology were grown via mixed-source hyd...

    Suhyun Mun, Seonwoo Park, Min Yang, Won Bae Cho in Journal of the Korean Physical Society (2024)

  20. No Access

    Article

    Design of a uniform current density transcranial direct current stimulation device with a multi-layer stepped conductivity sponge

    Transcranial direct current stimulation (tDCS) is a noninvasive method of brain modulation that is increasingly used to treat neuropsychiatric disorders and enhance cognitive capacity. Computational modeling p...

    **guang Feng, ByeongGeon Kim in Journal of Mechanical Science and Technology (2024)

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