2,957 Result(s)
-
Article
Open AccessMUC16 as a serum-based prognostic indicator of prometastatic gastric cancer
Metastatic gastric cancer (GC) presents significant clinical challenges due to its poor prognosis and limited treatment options. To address this, we conducted a targeted protein biomarker discovery study to id...
-
Article
Open AccessChildhood adversity and suicidal ideation in older Korean adults: unraveling the mediating mechanisms of mental health, physical health, and social relationships
Suicide rates in older adults are much higher than those in younger age groups. Given the rapid increase in the proportion of older adults in Korea and the high suicide rate of this age group, it is worth inve...
-
Article
The weldability in dissimilar joints of AA5052 and SPFC780DP steel by hybrid friction stir welding
The dissimilar welding of aluminum alloy and steel has become increasingly attractive in the automotive industry for achieve lightweight components. However, welding of these dissimilar materials is difficult ...
-
Article
Identification of maximal tumor size associated with negligible lymph node metastasis for endoscopic submucosal dissection of undifferentiated-type early gastric cancer
When treating undifferentiated-type early gastric cancer (UD-EGC) that is limited to the mucosa (clinically T1a), endoscopic submucosal dissection (ESD) can be considered if the tumor is 2 cm or less and is no...
-
Article
Pharmacokinetics and extensive intestinal first-pass effects of apigenin and its active metabolite, apigenin-7-O-glucuronide, in rats
This study investigated the metabolism and pharmacokinetics of apigenin and its metabolite, apigenin-7-O-glucuronide (A7G), using a newly developed UPLC-MS/MS method.
-
Article
Open AccessLimited impact of bacterial virulence on early mortality risk factors in Acinetobacter baumannii bacteremia observed in a Galleria mellonella model
Acinetobacter baumannii (AB) has emerged as a major pathogen in vulnerable and severely ill patients. It remains unclear whether early mortality (EM) due to AB bacteremia is because of worse clinical characterist...
-
Article
Anesthetic management of a patient with spinal and bulbar muscular atrophy (Kennedy’s disease)
-
Article
Open Access2023 Korean Society of Echocardiography position paper for the diagnosis and management of valvular heart disease, part II: mitral and tricuspid valve disease
This manuscript represents the official position of the Korean Society of Echocardiography on valvular heart diseases. This position paper focuses on the diagnosis and management of valvular heart diseases wit...
-
Article
Non-Mitochondrial Aconitase-2 Mediates the Transcription of Nuclear-Encoded Electron Transport Chain Genes in Fission Yeast
Aconitase-2 (Aco2) is present in the mitochondria, cytosol, and nucleus of fission yeast. To explore its function beyond the well-known role in the mitochondrial tricarboxylic acid (TCA) cycle, we conducted ge...
-
Article
Open AccessDifferential impacts of clinical, anatomical, and procedural factors on early and late mortality following open thoracoabdominal aortic repair: a retrospective observational study
The operative outcomes of thoracoabdominal aortic aneurysms (TAAAs) are challenged by high operative mortality and disabling complications. This study aimed to explore the baseline clinical, anatomical, and pr...
-
Article
Correlation of LLT-1 and NLRC4 inflammasome and its effect on glioblastoma prognosis
LLT-1 is a well-known ligand for the natural killer (NK) cell inhibitory receptor NKRP1A. Here, we examined NLRC4 inflammasome components and LLT-1 expression in glioblastoma (GBM) tissues to elucidate potenti...
-
Article
Open AccessDesensitizing efficacy of a universal dentin adhesive containing mesoporous bioactive glass on dentin hypersensitivity: a randomized clinical trial with a split-mouth model
This split-mouth blinded randomized controlled study compared the efficacy of a desensitizing agent with oxalate/resin polymer and a universal adhesive containing mesoporous bioactive glass (MBG) for dentin hy...
-
Article
Open AccessRed2Flpe-SCON: a versatile, multicolor strategy for generating mosaic conditional knockout mice
Image-based lineage tracing enables tissue turnover kinetics and lineage potentials of different adult cell populations to be investigated. Previously, we reported a genetic mouse model system, Red2Onco, which ec...
-
Article
Open AccessEvaluation of bovine coronavirus in Korean native calves challenged through different inoculation routes
Bovine coronavirus (BCoV) is a pneumoenteric virus that can infect the digestive and respiratory tracts of cattle, resulting in economic losses. Despite its significance, information regarding BCoV pathogenesi...
-
Article
Open AccessComparing two mucin secretagogues for the treatment of dry eye disease: a prospective randomized crossover trial
This study aimed to compare the clinical efficacy and investigate patients’ preferences for two mucin secretagogues in the treatment of dry eye disease (DED). Thirty patients with DED were randomly treated wit...
-
Article
Human adipose-derived stem cells genetically programmed to induce necroptosis for cancer immunotherapy
Herein, we present human adipose-derived stem cells (ADSCs) inserted with the receptor-interacting protein kinase-3 (RIP3) gene (RP@ADSCs), which induces cell necroptosis, for tumor immunotherapy. Necroptosis ...
-
Article
Open AccessSUnSeT: spectral unmixing of hyperspectral images for phenoty** soybean seed traits
Hyperspectral features enable accurate classification of soybean seeds using linear discriminant analysis and GWAS for novel seed trait genes.
-
Article
Association of Cough Severity with Asthma Control and Quality of Life in Patients with Severe Asthma
Symptoms are important components in determining asthma control and in the adjustment of treatment levels. However, clinical relevance of cough in severe asthma is not well-understood. This study aimed to eval...
-
Article
HVPE growth of Si crystal with topological chiral morphology
Topological chiral occurs when a crystal has an asymmetric structure that does not overlap with the mirror image. In this study, Si crystals with a topological chiral morphology were grown via mixed-source hyd...
-
Article
Design of a uniform current density transcranial direct current stimulation device with a multi-layer stepped conductivity sponge
Transcranial direct current stimulation (tDCS) is a noninvasive method of brain modulation that is increasingly used to treat neuropsychiatric disorders and enhance cognitive capacity. Computational modeling p...