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Reference Work Entry In depth
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Living Reference Work Entry In depth
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Article
Gene expression in archived newborn blood spots distinguishes infants who will later develop cerebral palsy from matched controls
Gene expression in archived newborn blood spots remaining from newborn screening may reflect pathophysiological disturbances useful in understanding the etiology of cerebral palsy (CP).
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Article
Renal Cell Carcinoma Deep Sequencing: Recent Developments
Renal cell carcinoma (RCC) is the most common type of renal cancer in adults. RCC is notoriously resistant to current therapies suggesting the need to improve our knowledge and create more effective therapies....
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Article
Exome sequencing of liver fluke–associated cholangiocarcinoma
Bin Tean Teh and colleagues report exome sequencing of Opisthorchis viverrini–related cholangiocarcinoma, a fatal bile duct cancer associated with liver fluke infection.
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Article
Correction: Corrigendum: Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
Nature 469, 539–542 (2011) In this Letter, the accession number for the gene expression data in the Gene Expression Omnibus was wrongly published as GEO22316. The correct accession number is GSE22316. We thank...
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Article
Molecular classification of breast phyllodes tumors: validation of the histologic grading scheme and insights into malignant progression
Phyllodes tumors of the breast are rare fibroepithelial neoplasms with a potential for recurrence. Current histological classification is not always predictive of clinical behavior. The aim of this study was t...
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Article
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
Using large-scale exome sequencing, Andrew Futreal and colleagues have identified a second frequently mutated gene (after VHL) in clear cell renal cell carcinomas, the most frequent type of kidney cancer. PBRM1, ...
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Article
Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes
A large survey for somatic mutations in clear cell renal cell carcinomas, the most common form of adult kidney cancer, shows that in addition to the known inactivating mutations in the VHL gene, recurrent mutatio...
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Reference Work Entry In depth
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Reference Work Entry In depth
MET