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Article
Open AccessRole of p53 isoforms in the DNA damage response during Drosophila oogenesis
The tumor suppressor p53 is involved in the DNA damage response and induces cell cycle arrest or apoptosis upon DNA damage. Drosophila p53 encodes two isoforms, p53A and p53B, that induce apoptosis in somatic cel...
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Article
Extremum seeking control using a partial sum of input-output product
Recent extremum seeking control that uses a continuous perturbation and the integral feedback of perturbation- output product is based on a static nonlinear process. The method can be applied to dynamic nonlin...
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Article
Control of a reactive batch distillation process using an iterative learning technique
Quadratic criterion-based iterative learning control (QILC) was applied to a numerical reactive batch distillation process, in which methacrylic anhydride (MAN) is produced through the reaction of methacrylic ...
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Article
TRAIL negatively regulates VEGF-induced angiogenesis via caspase-8-mediated enzymatic and non-enzymatic functions
Solid tumors supply oxygen and nutrients required for angiogenesis by producing vascular endothelial growth factor (VEGF). Thus, inhibitors of VEGF signaling abrogate tumor angiogenesis, resulting in the suppr...
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Article
Open AccessKurarinone promotes TRAIL-induced apoptosis by inhibiting NF-κB-dependent cFLIP expression in HeLa cells
This study was designed to investigate the effects of the prenylated flavonoid kurarinone on TNF-related apoptosis inducing ligand (TRAIL)-induced apoptosis and its underlying mechanism. A low dose of kurarino...
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Article
Molecular dynamics study of the role of friction on the thermal rupture of linear alternate copolymers
We investigated, using extensive molecular dynamics simulations, the role of friction on the thermal rupture of a linear alternating copolymer tethered at one end and pulled by a constant tensile force at the ...
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Article
Parameter estimation and dynamic control analysis of central carbon metabolism in Escherichia coli
The central carbon metabolic pathway is the most important among metabolic pathways in all microorganisms since it produces energy and precursors for biosynthesis. In this study, a dynamic model for central ca...
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Article
Combined run-to-run and LQG control of a 12-inch RTP equipment
A combined run-to-run (R2R) and LQG control method has been proposed for rapid thermal processing (RTP) equipment for run-wise improvement and real-time multivariable control of the temperature uniformity over...
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Article
Model predictive control of condensate recycle process in a cogeneration power station: Controller design and numerical application
A model predictive control (MPC) system has been developed for application to the condensate recycle process of a 300 MW cogeneration power station of the East-West Power Plant, Gyeonggido, Korea. Unlike other...
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Article
Repetitive control of CATOFIN process
The CATOFIN process is a propane dehydrogenation process for production of propylene. It uses multiple adiabatic fixed-bed reactors where dehydrogenation and regeneration (decoking) are performed alternatively...
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Article
The use of cubic spline and far-side boundary condition for the collocation solution of a transient convection-diffusion problem
Cubic spline collocation method with the far-side boundary condition has been proposed as a numerical method for the convection-dominant convection-diffusion problem. It has been shown that the proposed method...
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Article
Run-to-run control of inductively coupled C2F6 plasma etching of SiO2: Multivariable controller design and numerical application
A model-based run-to-run control method has been devised for an inductively coupled plasma etcher and applied to a numerical process for etching SiO2 film with C2F6 plasmas. The controller was designed to minimiz...
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Article
Run-to-run control of inductively coupled C2F6 plasma etching of SiO2: Construction of a numerical process with a computational fluid dynamics code
A numerical process to simulate SiO2 dry etching with inductively coupled C2F6 plasmas has been constructed using a commercial CFD code as a first step to design a run-to-run control system. The simulator was fou...
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Article
Nonlinear model-based repetitive control of simulated moving bed process
The simulated moving bed (SMB) process, after more than 40 years of successful operation in the petro-chemical industry, has emerged as one of the most important separation processes in the pharmaceutical, fin...
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Article
Control of pH neutralization process using simulation based dynamic programming
The pH neutralization process has long been taken as a representative benchmark problem of nonlinear chemical process control due to its nonlinearity and time-varying nature. For general nonlinear processes, i...
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Article
Methods for performance monitoring and diagnosis of multivariable model-based control systems
Methods for performance monitoring and diagnosis of multivariable closed loop systems have been proposed aiming at application to model predictive control systems for industrial processes. For performance moni...
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Article
Receding horizon control of cocurrent first order hyperbolic partial differential equation systems
Cocurrent first order hyperbolic partial differential equations (PDE’s) have finite impulse response (FIR) characteristics. A finite difference scheme that preserve these nice dynamic characteristics is recent...
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Article
Model predictive control of a fixed-bed reactor with nonlinear quality inference
A generic model predictive control framework has been proposed for a fixed-bed reactor with exothermic reaction. The proposed framework can conduct nonlinear inferential control of a product concentration toge...
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Article
Constrained digital regulation of hyperbolic PDE systems: A learning control approach
In this paper, exploiting repetitive properties, a constrained digital regulation technique for first order hyperbolic PDE systems is proposed that guarantees the stability and performance of the closed loop s...
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Article
Fuzzy control of ethanol concentration for emulsan production in a fed-batch cultivation ofAcinetobacter Calcoaceticus RAG-1
A fuzzy control system was organized and applied to the control of ethanol concentration in a fed-batch cultivation process for emulsan production byAcinetobacter calcoaceticus RAG-1. The membership functions and...
