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Article
Open AccessFlawed conclusions on the Västerbotten Intervention Program by San Sebastian et .al
An evaluation of Västerbotten Intervention Programme (VIP) was recently conducted by San Sebastian et al. (BMC Public Health 19:202, 2019). Evaluation of health care interventions of this kind require 1) an un...
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Article
Open AccessLongitudinal 10-year changes in dietary intake and associations with cardio-metabolic risk factors in the Northern Sweden Health and Disease Study
Dietary risks today constitute the largest proportion of disability-adjusted life years (DALYs) globally and in Sweden. An increasing number of people today consume highly processed foods high in saturated fat...
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Article
Open AccessCan BNP-guided therapy improve health-related quality of life, and do responders to BNP-guided heart failure treatment have improved health-related quality of life? Results from the UPSTEP study
To investigate whether B-type natriuretic peptide (NP)-guided treatment of heart failure (HF) patients improved their health related quality of life (Hr-QoL) compared to routine HF treatment, and whether chang...
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Article
Open AccessAssociations among 25-year trends in diet, cholesterol and BMI from 140,000 observations in men and women in Northern Sweden
In the 1970s, men in northern Sweden had among the highest prevalences of cardiovascular diseases (CVD) worldwide. An intervention program combining population- and individual-oriented activities was initiated...
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Article
Open AccessPrevalence of systemic immunoreactivity to Aggregatibacter actinomycetemcomitans leukotoxin in relation to the incidence of myocardial infarction
Chronic infections and associated inflammatory markers are suggested risk factors for cardiovascular disease (CVD). The proinflammatory cytokine, interleukin (IL)-1β, is suggested to play a role in the regulat...
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Article
Open AccessAtherosclerosis in early rheumatoid arthritis: very early endothelial activation and rapid progression of intima media thickness
In this study we aimed to investigate whether there are indications of premature atherosclerosis, as measured by endothelial dependent flow-mediated dilation (ED-FMD) and intima media thickness (IMT), in patie...
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Natriuretic Peptides
Natriuretic peptides are clinically used as biomarkers of heart failure and have in recent years become more and more valuable in the diagnosis of heart failure. B-type natriuretic peptide (BNP) and N-terminal...
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Article
The influence of acute-phase levels of haemostatic factors on reperfusion and mortality in patients with acute myocardial infarction treated with streptokinase
Background The fibrinolytic system and von Willebrand factor (vWF) have been shown to play a role as risk factors for myocardial infarction. We performed this prospective cohort study to ...
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Afferente Impulse in menschlichen Hautnerven