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  1. No Access

    Article

    Kidney function predicts new-onset cardiorenal events and mortality in primary aldosteronism: approach of the 2021 race-free eGFR equation

    Individuals with primary aldosteronism (PA) exhibit glomerular hyperfiltration, which may conceal underlying kidney damage. This observational cohort study enrolled 760 coronary artery disease-naive patients d...

    Chun-Fu Lai, Yen-Hung Lin, Kuo-How Huang, Jeff S. Chueh in Hypertension Research (2024)

  2. Article

    Open Access

    Propensity score matching analysis comparing radical prostatectomy and radiotherapy with androgen deprivation therapy in locally advanced prostate cancer

    To compare clinical outcomes between the use of robotic-assisted laparoscopic radical prostatectomy (RP) and radiotherapy (RT) with long-term androgen deprivation therapy (ADT) in locally advanced prostate can...

    Yu-Cheng Lu, Chao-Yuan Huang, Chia-Hsien Cheng, Kuo-How Huang in Scientific Reports (2022)

  3. Article

    Open Access

    Effect of diabetes mellitus and glycemic control on the prognosis of non-muscle invasive bladder cancer: a retrospective study

    Hyperglycemia is associated with series of process leading to oncogenesis. Evidence has shown that diabetes mellitus (DM) seems to be associated with poor prognosis in patients with bladder cancer. However, ev...

    Wei-Lun Huang, Kuo-How Huang, Chao-Yuan Huang, Yeong-Shiau Pu in BMC Urology (2020)

  4. Article

    Open Access

    Author Correction: Simvastatin reduces the carcinogenic effect of 3-methylcholanthrene in renal epithelial cells through histone deacetylase 1 inhibition and RhoA reactivation

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Chih-Cheng Chang, Kuo-How Huang, Sung-Po Hsu, Yuan-Chii G. Lee in Scientific Reports (2020)

  5. Article

    Open Access

    Preoperative %p2PSA and Prostate Health Index Predict Pathological Outcomes in Patients with Prostate Cancer Undergoing Radical Prostatectomy

    To evaluate the predictive accuracy of the %p2PSA and prostate health index (PHI) in predicting aggressive pathological outcomes in patients with prostate cancer (PCa) undergoing radical prostatectomy (RP), we...

    Yung-Ting Cheng, Chao-Yuan Huang, Chung-Hsin Chen, Shih-Ting Chiu in Scientific Reports (2020)

  6. Article

    Open Access

    Author Correction: Comparison of Multipulse Laser Vaporesection versus Plasmakinetic Resection for Treatment of Benign Prostate Obstruction

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Fu-Shun Hsu, Chen-Wei Chou, Hong-Chiang Chang, Yuan-Po Tu in Scientific Reports (2019)

  7. No Access

    Article

    Trifecta outcome of ureteral reconstruction in iatrogenic injury and non-iatrogenic ureteral lesions: a 10-year experience at a tertiary referral center

    To analyze the trifecta outcome (functional, anatomical, and surgical aspects) of surgical reconstruction for ureteral lesions and investigate the factors affecting the success rate of such reconstruction.

    Chi-Shin Tseng, Ting-En Tai, Chung-Hung Hong, Chung-Hsin Chen in World Journal of Urology (2019)

  8. Article

    Open Access

    The impact of primary location and age at orchiopexy on testicular atrophy for congenital undescended testis

    In this study, we investigated post-orchiopexy testicular growth of undescended testes (UDTs) at different primary locations and determined the risk factors for testicular atrophy (TA). We conducted a retrospe...

    Chi-Shin Tseng, Kuo-How Huang, Ming-Chieh Kuo, Chung-Hung Hong in Scientific Reports (2019)

  9. Article

    Open Access

    Comparison of Multipulse Laser Vaporesection versus Plasmakinetic Resection for Treatment of Benign Prostate Obstruction

    We aimed to compare the efficacy and safety of Multipulse laser vaporesection of the prostate (MPVP) versus plasmakinetic resection of the prostate (PKRP) for treatment of patients with benign prostate obstruc...

    Fu-Shun Hsu, Chen-Wei Chou, Hong-Chiang Chang, Yuan-Po Tu in Scientific Reports (2019)

  10. Article

    Open Access

    Simvastatin reduces the carcinogenic effect of 3-methylcholanthrene in renal epithelial cells through histone deacetylase 1 inhibition and RhoA reactivation

    The therapeutic effects of simvastatin for renal cell carcinoma (RCC) are controversial. In this study, the effects of simvastatin on the carcinogenic properties of 3-methylcholanthrene (3MC; an aryl-hydrocarb...

    Chih-Cheng Chang, Kuo-How Huang, Sung-Po Hsu, Yuan-Chii G. Lee in Scientific Reports (2019)

  11. Article

    Correction to: Trichostatin A, a histone deacetylase inhibitor, induces synergistic cytotoxicity with chemotherapy via suppression of Raf/MEK/ERK pathway in urothelial carcinoma

    In Fig. 1b, upper part, the cell viability counts after treatment with cisplatin and TSA in T24 cells was by mistake a duplication of the image for NTUB1 on the left. In the corrected version of Fig. 1, the im...

    Wei-Chou Lin, Fu-Shun Hsu, Kuan-Lin Kuo, Shing-Hwa Liu in Journal of Molecular Medicine (2019)

  12. No Access

    Article

    Comparison of single and tandem ureteral stenting for malignant ureteral obstruction: a prospective study of 104 patients

    The aim of this study was to compare single and tandem ureteral stenting in the management of malignant ureteral obstruction (MUO).

    Kao-Lang Liu, Bo-Ching Lee, Jian-De Ye, Yu-Hsuan Chang in European Radiology (2019)

  13. Article

    Open Access

    Factors Associated with Bothersome Lower Urinary Tract Symptoms in Middle-Aged Men Receiving Health Checkup

    The prospective study is to investigate the associations between serum testosterone levels and LUTS among middle-aged men ≥40 years receiving health check-up. Lower urinary tract symptoms were evaluated by the...

    Teng-Kai Yang, Chi-Chih Chang, Hong-Chiang Chang, Hung-Ju Yang in Scientific Reports (2019)

  14. No Access

    Article

    Trichostatin A, a histone deacetylase inhibitor, induces synergistic cytotoxicity with chemotherapy via suppression of Raf/MEK/ERK pathway in urothelial carcinoma

    In this study, we aimed to investigate the antitumor effects of trichostatin A (TSA), an antifungal antibiotic that inhibits histone deacetylase (HDAC) family of enzymes, alone or in combination with anyone of...

    Wei-Chou Lin, Fu-Shun Hsu, Kuan-Lin Kuo, Shing-Hwa Liu in Journal of Molecular Medicine (2018)

  15. Article

    Open Access

    Risk of sepsis in patients with primary aldosteronism

    The interaction between hyperaldosteronism and immune dysfunction has been reported and glucocorticoid co-secretion is frequently found in primary aldosteronism (PA). The aforementioned conditions raise the po...

    Chieh-Kai Chan, Ya-Hui Hu, Likwang Chen, Chin-Chen Chang, Yu-Feng Lin in Critical Care (2018)

  16. Article

    Open Access

    The influence of the peripheral cortisol fluctuation on the success rate of adrenal venous sampling

    In this retrospective study, we aimed to estimate the influence of fluctuating peripheral plasma cortisol concentration (PCC) on the success rate of non-stimulated adrenal venous sampling (AVS) and to demonstr...

    Chin-Chen Chang, Bo-Ching Lee, Kao-Lang Liu, Yeun-Chung Chang in Scientific Reports (2018)

  17. Article

    Open Access

    Advantage of early orchiopexy for undescended testis: Analysis of testicular growth percentage ratio in patients with unilateral undescended testicle

    This study reports the experience of our tertiary referral center and proposes a new indicator, the growth percentage ratio (GPR), for determining the optimal timing of surgical intervention. A retrospective r...

    Chi-Shin Tseng, I-Ni Chiang, Chung-Hung Hong, Yu-Chuan Lu in Scientific Reports (2017)

  18. No Access

    Article

    Comparison of C-arm computed tomography and on-site quick cortisol assay for adrenal venous sampling: A retrospective study of 178 patients

    To compare the performance of on-site quick cortisol assay (QCA) and C-arm computed tomography (CT) assistance on adrenal venous sampling (AVS) without adrenocorticotropic hormone stimulation.

    Chin-Chen Chang, Bo-Ching Lee, Yeun-Chung Chang, Vin-Cent Wu in European Radiology (2017)

  19. Article

    Open Access

    Induction of sirtuin-1 signaling by resveratrol induces human chondrosarcoma cell apoptosis and exhibits antitumor activity

    Chondrosarcoma is a malignant primary bone tumor. Sirtuin-1 (SIRT1), which is a member of sirtuin family, plays a dual role either in cancer promotion or suppression. There is no report about the role of SIRT1...

    Sung-Chuan Chao, Ying-Ju Chen, Kuo-How Huang, Kuan-Lin Kuo in Scientific Reports (2017)

  20. Article

    Open Access

    The prevalence of CTNNB1 mutations in primary aldosteronism and consequences for clinical outcomes

    Constitutive activation of the Wnt pathway/β-catenin signaling may be important in aldosterone-producing adenoma (APA). However, significant gaps remain in our understanding of the prevalence and clinical outc...

    Vin-Cent Wu, Shuo-Meng Wang, Shih-Chieh Jeff Chueh, Shao-Yu Yang in Scientific Reports (2017)

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