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Article
Retrospectively diagnosed autoimmune VWF deficiency in a patient with repeated hemorrhagic events after two common colds
Autoimmune von Willebrand factor (VWF) deficiency (AiVWFD) caused by anti-VWF autoantibodies is a rare bleeding disorder, whereas “non-immune” acquired von Willebrand syndrome (AVWS) caused by other etiologies...
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Article
A case of cholangiocarcinoma complicating liver abscess-related tumor thrombus extending via the inferior vena cava to the right ventricle and visualized on transthoracic echocardiography
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Article
Laparoscopic hepatectomy for hepatocellular carcinoma in patients with hemophilia A and B: a report of two cases
Hepatocellular carcinoma (HCC) is a life-threatening complication of hemophilia. Reports of patients with hemophilia undergoing hepatectomy for HCC are scarce. We report the cases of patients with hemophilia A...
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Article
Chronic left ventricular apical thrombosis complicating isolated left ventricular noncompaction in a patient with human immunodeficiency virus infection
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Article
Successful treatment of Japanese hemophilia patient co-infected with HIV and HCV genotype 4a by glecaprevir/pibrentasvir therapy
Although direct-acting antiviral (DAA)-based anti-hepatitis C virus (HCV) therapies are very effective for patients with genotypes 1 and 2, evidence of the efficacy of DAA-based therapy for the special populat...
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Article
Methicillin-resistant Staphylococcus aureus-induced right-sided infective endocarditis detected by transthoracic echocardiography: the importance of parasternal short-axis view screening
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Article
Overshoot of FVIII activity in patients with acquired hemophilia A who achieve complete remission
Acquired hemophilia A (AHA) is a rare, life-threatening bleeding disorder caused by autoantibodies against coagulation factor VIII (FVIII). Immunosuppressive therapy for AHA aims to arrest bleeding by eliminat...
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Article
Successful hemostatic management of major surgery for cervical spondylotic myelopathy in a patient with severe factor XI deficiency
Factor XI deficiency (FXID) is a rare bleeding disorder caused by mutations in the F11 gene. Spontaneous bleeding in patients with factor XI deficiency is rare, but major bleeding may occur after surgery or traum...
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Article
Darunavir concentration in PBMCs may be a better indicator of drug exposure in HIV patients
The clinical efficacies of some antiretroviral drugs are known to not depend on its concentration in blood. To establish a method of dosage adjustment for darunavir (DRV) based on pharmacokinetic theory, we an...
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Article
Clinical characteristics and outcomes of acquired hemophilia A: experience at a single center in Japan
Acquired hemophilia A (AHA), which is caused by autoantibodies against coagulation factor VIII (FVIII) is a rare, life-threatening bleeding disorder, the incidence of which appears to be increasing in Japan as...
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Article
Successful management of perioperative hemostasis in a patient with Glanzmann thrombasthenia who underwent a right total mastectomy
Perioperative hemostatic management is a challenge in patients with Glanzmann thrombasthenia (GT). The standard means of preventing surgical bleeding in GT patients is platelet transfusion. However, GT patient...
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Article
Water intoxication associated with moderate dose of cyclophosphamide pulse therapy in an elderly patient: a case report and literature review
Intravenous high-dose cyclophosphamide infusion, usually performed to treat malignant neoplasms, is known to cause water intoxication. Intravenous cyclophosphamide pulse therapy (IVCY) is increasingly being em...
