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Article
Vitamin D Relieves Epilepsy Symptoms and Neuroinflammation in Juvenile Mice by Activating the mTOR Signaling Pathway via RAF1: Insights from Network Pharmacology and Molecular Docking Studies
Epilepsy is a common neurological disorder, and the exploration of potential therapeutic drugs for its treatment is still ongoing. Vitamin D has emerged as a promising treatment due to its potential neuroprote...
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Article
Open AccessThe EV71 2A protease occupies the central cleft of SETD3 and disrupts SETD3-actin interaction
SETD3 is an essential host factor for the replication of a variety of enteroviruses that specifically interacts with viral protease 2A. However, the interaction between SETD3 and the 2A protease has not been f...
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Article
Open AccessA patient with multiple primary malignant neoplasms with high variant allele frequencies of RB1, TP53, and TERT
Multiple primary malignant neoplasms are a rare disease with tumors of different histology or morphology arising in various sites. Next-generation sequencing is essential in the etiology, diagnosis, treatment,...
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Article
Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute
Argonaute (Ago) proteins mediate RNA- or DNA-guided inhibition of nucleic acids1,2. Although the mechanisms used by eukaryotic Ago proteins and long prokaryotic Ago proteins (pAgos) are known, that used by short ...
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Article
Open AccessHypertension and cystatin C account for sex differences in serum homocysteine levels in acute coronary syndrome subjects with normal serum creatinine
Hyperhomocysteinemia is one of cardiovascular disease risk factors and fasting homocysteine levels are significantly elevated in male compared to female acute coronary syndrome (ACS) patients with normal renal...
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Article
3-Methyladenine ameliorates surgery-induced anxiety-like behaviors in aged mice by inhibiting autophagy-induced excessive oxidative stress
Postoperative anxiety is a common surgical complication in older patients. Research has recently linked excessive autophagy to several neurological disorders, including anxiety. This study aimed to determine w...
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Article
Open AccessSLC27A2 mediates FAO in colorectal cancer through nongenic crosstalk regulation of the PPARs pathway
Peroxisome proliferator activated receptors (PPARs) are a nuclear hormone receptors superfamily that is closely related to fatty acid (FA) metabolism and tumor progression. Solute carrier family 27 member 2 (SLC2...
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Chapter
Research Applications of Positron Emission Tomography/Magnetic Resonance (PET/MR) Imaging in Epilepsy
Epilepsy is a neurological condition involving recurrent seizures that are induced by abnormal neuronal discharges in the brain. According to statistics, there are approximately 6.5 million individuals with ep...
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Article
Estimation of soil lead content based on GF-5 hyperspectral images, considering the influence of soil environmental factors
Heavy metal pollution is an increasingly serious problem. The accumulation of heavy metals in soil is a threat to ecological balance and human health, and therefore, it is very important to monitor heavy metal...
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Chapter and Conference Paper
DuDoTrans: Dual-Domain Transformer for Sparse-View CT Reconstruction
While Computed Tomography (CT) is necessary for clinical diagnosis, ionizing radiation in the imaging process induces irreversible injury, thereby driving researchers to study sparse-view CT reconstruction. It...
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Article
Assessment of localization accuracy and postsurgical prediction of simultaneous 18F-FDG PET/MRI in refractory epilepsy patients
To evaluate the accuracies of simultaneous 18F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ([18F]-FDG PET/MRI) in preoperative localization and the postsurgical prediction.
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Article
Crossed cerebellar diaschisis: risk factors and prognostic value in focal cortical dysplasia by 18F-FDG PET/CT
Crossed cerebellar diaschisis (CCD) has been widely studied in hemispheric stroke but is less characterized in epilepsy. In this study, we used 18F-FDG PET/CT to investigate the risk factors for CCD and its progn...
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Article
Fibre optic sensors for the monitoring of rotating electric machines: a review
Accurate and efficient monitoring of electrical machine (EM) operating parameters, including temperature, mechanical vibration, torque and rotating speed and others that can indicate the EM health conditions i...
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Chapter and Conference Paper
Improving Generalizability in Limited-Angle CT Reconstruction with Sinogram Extrapolation
Computed tomography (CT) reconstruction from X-ray projections acquired within a limited angle range is challenging, especially when the angle range is extremely small. Both analytical and iterative models nee...
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Article
Deep Vein Thrombosis in Patients with Intertrochanteric Fracture: A Retrospective Study
This study aimed to investigate the incidences of pre- and post-operative lower extremity deep venous thrombosis (DVT) in hospitalized patients with intertrochanteric fractures and to analyze the relevant risk...
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Article
Open AccessNonoperative treatment versus volar locking plate fixation for elderly patients with distal radial fracture: a systematic review and meta-analysis
This systematic review and meta-analysis assessed the role of nonoperative treatment and volar locking plate (VLP) fixation in elderly patients with distal radial fracture.
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Article
Comparison of posterior ring fixation with combined anterior and posterior ring fixation for the treatment of lateral compression type 2 pelvic fractures
The aim of surgical treatment for lateral compression type 2 (LC-2) pelvic fractures is to enable early mobilization and provide pain relief. Anterior and posterior ring fixation is usually performed simultane...
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Article
Open AccessLong non-coding RNA H19, a novel therapeutic target for pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with high mortality, which threats peoples’ health. Unfortunately, the pathogenesis of PDAC remains unclear. Recent studies have indicated th...
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Article
Complete Genome Sequence of Strain YCSC6, a Marine Bacterium Isolated from Saturated Saltpan with Activity Against Uronema marinum
Salinivibrio proteolyticus strain YCSC6 was isolated from a saturated saltpan and demonstrated to have strong insecticidal activity against turbot’s pathogenic ciliate—Uronema marinum. In this study, we sequenced...
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Article
Ciliate Uronema marinum is the causative agent of scuticociliatosis in farm raised turbot Scophthalmus maximus
To identify the pathogen that causes scuticociliatosis in farmed-raised turbot Scophthalmus maximus, we isolated a ciliate from the brain tissue of an infected turbot and identified it as Uronema marinum based on...
